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This chapter provides useful guidelines for the immunophenotypic identification of both indolent and aggressive B-cell lymphomas. An integrated diagnostics is necessary to provide the final classification, but flow cytometry allows for a quick orientation about the lymphoma subtype and may help in speeding targeted further assays and therapeutic decisions.
This chapter explores the intersection of property law and consumer protection in the digital age, particularly in the context of purchasing technological or digital goods. The unique nature of transactions involving autonomous vehicles, drones, robot-chefs, smart appliances, and eBooks raises questions about the traditional understanding of property rights. While existing critiques often rely on contract law and consumer protection regulations, this chapter argues for the affirmative use of property law in addressing the challenges posed by the restricted usability and alienability of digital products. The prevailing assumption that property law is unsuitable for such issues is challenged, and the chapter advocates for a theoretical and normative shift. By analyzing the regulation and management of technological property through a property law lens, the chapter proposes a new perspective and outlines a roadmap for understanding and addressing the property challenges inherent in the digital consumer landscape.
This is by far the longest chapter in the book. It takes the archaeological picture and returns to the biblical material, as analyzed critically in Chapter 2. Putting names and details to the generalities, it shows how the move to centralized sites fits with the biblical picture of Saul, the expansion of the highland polity into the surrounding areas fits with the biblical picture of David, and the building program plus investment in copper mining fits with that of Solomon. The chapter delves into many specifics such as the evidence from Khirbet Qeiyafa, David’s competition with Ish-Boshet, and the list of Solomon’s officials. It uses both minute archaeological information and specific details from the biblical descriptions to present a thorough reconstruction of the sociopolitical developments of the tenth century, and of the kingdoms of Saul, David and Solomon.
This chapter compares the short-lived norm recognition in the lead-up to the 2003 Iraq war with the persistent norm recognition in the 1267 sanctions regime. Delegation to agents – weapons inspectors (Iraq) and the Ombudsperson (1267 sanctions regime) – played a significant role due to its consensual and potentially ongoing nature. The chapter thus focuses on how delegation affects the relative stability of norm recognition. The different problem structures both agents faced made the Ombudsperson more effective in managing norm contestation than the United Nations (UN) weapons inspectors: Certainty over the output legitimacy of its work and compliance constituencies that exert social pressure on the UN Security Council (UNSC) to continue delegating have made it easier to build a reputation as credible and effective. While norm recognition persists, the indirect costs of delegation for the UNSC have led to tensions in the delegation relationship, rendering resolution of the claim disagreement between the UNSC and European Court of Justice (ECJ) unlikely. Moreover, the chapter shows that contestation over the 2003 Iraq war reduced the clarity, and thus the social strength, of chapter VII norms, but contestation increased the social strength of due process rights in targeted sanctions. The effect on relative norm strength is more difficult to determine due to the claim disagreement.
The EU is attempting to indirectly regulate the Internet of Things by improving access to data through a cross-sectoral data governance framework. On the face of it, recent EU data governance laws – Data Governance Act, Digital Markets Act, Digital Services Act, AI Act – go in the direction of more open, accessible, and reusable data. However, they tend to balance that ethos with provisions that IoT big tech can use to retain and strengthen data enclosures. This chapter aims to critically assess whether the attempt to balance openness and IP results in the prevalence of closed IoT systems, thus ultimately preventing smart data from reuse that would otherwise benefit society at large.
Hodgkin lymphoma, a nodal disease, is usually diagnosed using morphology and immunochemistry on lymph nodes biopsies. However, with the increased practice of fine-needle aspiration or core biopsy, multiparameter flow cytometry (MFC) can provide valuation information on cell suspensions from such samples. Here, the major markers and characteristics allowing, in MFC, to distinguish between the scarce Reed Sternberg cells and the inflammatory immunological infiltrate surrounding them are described. Guidelines and recent information are provided for readers willing to implement these investigations in their own settings.
The auction of Bored Ape #8817 for $3.4 million in October 2021 marked a watershed moment in the escalating trend of non-fungible tokens (NFTs). This chapter ventures into the core of the tokenization phenomenon, scrutinizing the legal implications of creating digital representations (tokens) of diverse assets. Amid the burgeoning NFT market, a pivotal question emerges: What precisely are the property rights conferred upon those acquiring these tokens? Beyond the staggering sales figures, the chapter dissects the tokenization process, emphasizing the NFT minting process and blockchain technology. It explores claims that NFTs herald the future of digital property, challenging traditional governmental powers. Anticipating legal challenges, the chapter navigates critical inquiries about token holders’ rights, the tethering (or not) of tokens to underlying assets, and the impact of the 2022 Uniform Commercial Code revisions. This chapter seeks to provide a nuanced perspective, unraveling legal realities from the fervor surrounding tokenization’s transformative potential in the digital era.