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Broaching the topic of drugs and drug use with your child can feel particularly daunting. With the illegal drug market constantly evolving, it can be difficult to stay up to date with the latest information. How to Talk to Your Child About Drugs is an evidence-based, practical guide from a leading addiction specialist. The book offers clear and accessible guidance for parents on how to have effective conversations with their child about this difficult topic. It provides a summary of both established and newly emerging drugs, how drugs work in the brain, how they cause harm, and why some people are more vulnerable than others to problems, including signs parents should be looking out for. This is a book that all parents will need at some stage. It will help you feel better informed about drugs, more confident in talking to your child, and better equipped to tackle any problems.
Legal, financial, and regulatory barriers that may hinder the innovation, establishment, and operationalization of nature-based eco-ventures in the Middle East and North Africa (MENA) region must be carefully examined and addressed. While several studies have examined the importance of eco-entrepreneurship as a tool for halting biodiversity loss, an in-depth examination of the legal and policy barriers that hinder the growth of small and medium eco-enterprises (SMEEs) has remained absent. This chapter fills a gap in this regard. It examines the strategic transformations of biodiversity law and policy that are required to promote these pro-biodiversity, nature-based-SMEEs across the region. After developing a profile of law and governance barriers facing nature-based-SMEEs in the region, it proposes dynamic legal solutions for addressing such barriers.
Edited by
James Ip, Great Ormond Street Hospital for Children, London,Grant Stuart, Great Ormond Street Hospital for Children, London,Isabeau Walker, Great Ormond Street Hospital for Children, London,Ian James, Great Ormond Street Hospital for Children, London
Anaesthesia for paediatric urology may be for minor to major complex surgery. In this chapter, we discuss the anaesthetic management of a subspecialty that allows for a variety of general and regional anaesthetic techniques to be applied. Minor procedures include cystoscopy, resection of posterior urethral valves, circumcision, insertion of suprapubic (SP) lines, hypospadias repair and orchidopexy. We discuss techniques for major surgery, including pyeloplasty, ureteric re-implantation, nephrectomy, resection of Wilms tumour (nephroblastoma), bladder exstrophy and epispadias repair, bladder augmentation (ileocystoplasty) and formation of Mitrofanoff, as well as renal transplantation. Preoperatively, children undergoing cystoscopy and major urological and reconstructive surgery require a urine culture to guide antibiotic prophylaxis. Local ‘maximum surgical blood ordering schedules’ should be followed for guidance regarding cross-matching of blood for major procedures. Close communication with the surgeon and wider multidisciplinary team is necessary to identify the extent of surgery, positioning and appropriate vascular access for complex surgery and renal transplantation.
Edited by
James Ip, Great Ormond Street Hospital for Children, London,Grant Stuart, Great Ormond Street Hospital for Children, London,Isabeau Walker, Great Ormond Street Hospital for Children, London,Ian James, Great Ormond Street Hospital for Children, London
The League’s conference on the codification of international law opened in The Hague in 1930, vested with responsibility for producing (among other things) a treaty on territorial waters. Two major issues gave rise to disagreement: the breadth of territorial waters, with some states arguing for their extension according to local circumstances; and the contiguous zone, with some states claiming limited jurisdiction over customs, immigration, security and fishing zones. The British, as the self-proclaimed guarantors of the freedom of the seas, took a hard line against both ideas, holding out for three-mile territorial waters without a contiguous zone. They could not compel most other states to agree to this – a symptom of their decline as the leading maritime power – but neither could the other states compel the British to accept their positions. This impasse resulted in the committee’s failure to settle either issue, or to produce a treaty.
Chapter 2 considers the historical context from which today’s station hustle has emerged as a distinct economic logic and mode of production. It relates the station’s contemporary workings to the history of local economic practices and the wider political and economic changes that have shaped commercial road transport since the early days of motorisation in the early twentieth century, emphasising the role that bus stations have played in these developments. It shows how local transport operators have long harnessed the logics of risk, competition, and shrewd resourcefulness as the principal properties of economic organisation and action, features that have allowed them to both capitalise on and compensate for the weakness of the services provided by the state. The ways in which they have accommodated the effects of state regulatory intervention are consistent with these logics: in most cases, state intervention has been considered just another element of market volatility.
Edited by
James Ip, Great Ormond Street Hospital for Children, London,Grant Stuart, Great Ormond Street Hospital for Children, London,Isabeau Walker, Great Ormond Street Hospital for Children, London,Ian James, Great Ormond Street Hospital for Children, London
Anaesthesia for thoracic surgery in children poses a variety of challenges for the paediatric anaesthetist, who will encounter problems different from those faced in adult practice. It is a low-volume surgical speciality, thus predominantly confined to specialist paediatric centres with anaesthesia required for a heterogenous range of conditions. One-lung ventilation may often be required, and knowledge of the techniques used for the varying size of the paediatric airway is essential. The impact of patient positioning, surgical retraction of the lung and the underlying disease process poses further challenges to the paediatric anaesthetist. This chapter covers management of the most common paediatric specific disease processes, including congenital and acquired lung abnormalities, intrathoracic masses, intrapleural collections and pectus surgery with an emphasis on lung isolation techniques and perioperative analgesia, including regional anaesthesia.
Although a product of his time – the literary traditions of Pope, Addison, and Swift; the Toryism and churchmanship of the eighteenth century – Samuel Johnson also transcended it through his own gifts and forceful character. After a difficult early life, marked by melancholy, a troubled relationship with his family, and an early departure from Oxford University, Johnson began to find his way in the 1730s. He married Elizabeth Porter, moved to London, and began to make his mark through work at the Gentleman’s Magazine and works such as the Life of Savage. He achieved renown as an essayist and fame as the compiler of the Dictionary but also suffered from bereavement and continuing financial insecurity. After the award of a government pension in 1762, Johnson’s works have a more relaxed style, and his final major work, the Lives of the Poets, helped to establish this era as the Age of Johnson.
This chapter examines the legal and institutional framework on access and benefit sharing (ABS) in the Middle East and North Africa (MENA) region. It examines the drivers and dimensions of access and benefit sharing risks in the MENA region, gaps in existing legal frameworks on ABS in the region, and innovative approaches for addressing such gaps. The chapter delves into the challenges of ABS in the MENA region. The Nagoya Protocol’s principles of access to genetic resources and benefit sharing are highlighted, underscoring their significance in the MENA context. Given the fragile nature of global biodiversity, it is crucial to support and innovatively implement these existing regulations, ensuring an effective and efficient approach to ABS.
This chapter starts by providing historical perspective on the evolution of the Polish regulatory framework for the protection of utility models. Interestingly, the draft IPL takes us to legislative solutions already tested in the past. One might even say nihil novi sub sole (there is nothing new under the sun). The chapter presents data about the functioning of the regime currently in force. This is followed by a more general discussion, drawing on experience from other jurisdictions, of how various aspects of the regulatory framework might affect the ability of the system to promote innovation. Then, the current legislative framework is presented against the backdrop of the solutions proposed in the draft IPL.
Edited by
James Ip, Great Ormond Street Hospital for Children, London,Grant Stuart, Great Ormond Street Hospital for Children, London,Isabeau Walker, Great Ormond Street Hospital for Children, London,Ian James, Great Ormond Street Hospital for Children, London
The extensive thermodynamic variables of a fluid are introduced as the internal energy, volume, and number of molecules. The entropy is defined and also shown to be extensive. Taking the total derivative of the internal energy produces the first law of thermodynamics and defines the intensive parameters of temperature, pressure, and chemical potential. Changing variables from extensive variables to intensive variables is accomplished with the Legendre transform and defines alternative energies such as the Helmholtz free energy, enthalpy, and Gibbs free energy. Thermodynamic equilibrium requires that each element of a system have the same temperature, pressure, and chemical potential. For equilibrium to be stable, the material properties of each element must satisfy certain derived constraints. First-order phase transition are treated for a single-species system. Multispecies systems are treated and a widely used expression for how the chemical potentials of each species depend on the concentration of the species is derived. Chemical reactions are treated as is osmosis. The thermodynamics of solid systems is addressed along with mineral solubility in liquid solutions.
This chapter explores how Estonia became Europe’s top performer on PISA, without that being the goal. It unpacks social and education policies and practices and interventions that have helped build a high-equity high-performing education system. These include policies and initiatives fostering equity, inclusion, learner autonomy, teacher and school principal professionalism, autonomy and responsibility. Stakeholder engagement has led to longstanding cross-party agreements on the purpose of education. Thanks to investments into evidence- and results-based planning those agreements have been generative-productive. Eighteen months of paid job-protected parental leave encourages early responsive parenting. High levels of investment into preschool education help give children a good start in life. There are national curricula, but schools reinterpret those, creating their own curricula. Stakeholders and government took bold decisions such as the digitalisation of education at a point when the idea seemed utopian. They invested in free school meals, support for students in difficulty and voluntary formative assessment systems. No less important was a shift to favouring school self-evaluation over external inspections. In addition, the system generates substantial easily accessible and user-friendly data, including perceptions of well-being, autonomy and connectedness, not just examination results. This builds internal and external accountability and contributes to stakeholder collective efficacy.