Thousands of people will suffer and die this year because we do not donate enough substances of human origin, including blood plasma. To solve this, some recommend that we allow commercial organizations to assist in collecting these and that we permit donor compensation as a tool to encourage donations. Many object to these proposals, including for semiotic or expressive reasons. But insofar as these objections rely on meanings and these meanings are social constructs, we can revise the meaning of these practices to avoid commodification. Revision may work in principle, but in practice some complain that changing meanings may be too difficult or practically infeasible. This essay attempts to show that this is not so in a wide range of cases and uses the case of commercial compensated blood plasma collection as an illustration. Getting people to conceive of this practice not as payment for blood plasma but as compensation for the time, effort, and inconvenience associated with the giving of plasma is practically feasible and preferable to prohibition.