In this paper, we obtain some characterizations of the (strong) Birkhoff–James orthogonality for elements of Hilbert
${{C}^{*}}$-modules and certain elements of
$\mathbb{B}\left( H \right)$. Moreover, we obtain a kind of Pythagorean relation for bounded linear operators. In addition, for
$T\in \mathbb{B}(H)$ we prove that if the norm attaining set
${{\mathbb{M}}_{T}}$ is a unit sphere of some finite dimensional subspace
${{H}_{0}}$ of
$H$ and
$||T|{{|}_{{{H}_{0}}\bot }}\,<\,\,||T||$, then for every
$S\in \mathbb{B}(H)$,
$T$ is the strong Birkhoff–James orthogonal to
$S$ if and only if there exists a unit vector
$\xi \in {{H}_{0}}$ such that
$||T||\xi =\,|T|\xi $ and
${{S}^{*}}T\xi =0$. Finally, we introduce a new type of approximate orthogonality and investigate this notion in the setting of inner product
${{C}^{*}}$-modules.