The delivery of sedation to children presents a significant challenge to many clinicians from a variety of specialties on a daily basis [1]. While tremendous evidence exists to guide the clinician through the pharmacology, physiology, and medical issues involved, the final sedative regimen is most likely based on the specific training of the provider and the experience that the individual brings to the procedure [1]. Collectively, all providers tasked with providing sedation to children must acknowledge the inherent limitations of their experiences and training; only then can clinicians bring sober and intelligent judgment to this critical arena.