Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-6bf8c574d5-2jptb Total loading time: 0 Render date: 2025-02-14T23:27:03.415Z Has data issue: false hasContentIssue false

22 - Ovulation induction in women with polycystic ovary syndrome

from Section 4 - The tool kit

Published online by Cambridge University Press:  05 July 2015

By
Shawky Z. A. Badawy  and
Botros R. M. B. Rizk
Edited by
Leo Plouffe, Jr  and
Botros R. M. B. Rizk
Leo Plouffe, Jr
Affiliation:
Bayer Healthcare, Wayne, New Jersey
Botros R. M. B. Rizk
Affiliation:
University of South Alabama
Get access

Summary

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Androgens in Gynecological Practice , pp. 226 - 232
Publisher: Cambridge University Press
Print publication year: 2015

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Stein, IF, Leventhal, ML. Amenorrhea associated with bilateral polycystic ovaries. Am J Obstet Gynecol 1935;29:181–91.Google Scholar
2.Stein, IF. Duration of infertility following ovarian wedge resection. West J Surg 1964;72:237.Google Scholar
3.Goldzieher, JW, Axelrod, LR. Clinical and biochemical features of polycystic ovarian disease. Fertil Steril 1963;14:631–53.CrossRefGoogle ScholarPubMed
4.Rebar, R, Judd, HL, Yen, SSC, et al. Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. J Clin Invest 1976;57:1320–9.Google Scholar
5.Judd, H, Anderson, D, Yen, S. The effect of ovarian wedge resection on circulating gonadotropin and ovarian steroids levels in patients with polycystic ovary syndrome. J Clin Endocrinol Metab 1976;42:347–55.Google Scholar
6.Zawadski, JK, Dunaif, A. Diagnostic criteria for polycystic ovary syndrome towards a rational approach. In: Dunaif, A, Givens, JR, Haseltine, FP, Merriam, GR (Eds.) Polycystic Ovary Syndrome. Boston, MA: Blackwell Scientific Publications, 1992:377–84.Google Scholar
7.The Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Workshop Group. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovarian Syndrome. Human Reprod 2004;19:41–7.Google Scholar
8.The Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Workshop Group. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovarian Syndrome. Fertil Steril 2004; 81(1):19–25.CrossRefGoogle Scholar
9.Azziz, R, Carmina, E, Dewailly, D, et al. The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report. Fertil Steril 2009;91:456–88.CrossRefGoogle ScholarPubMed
10.Farah, L, Lozenby, AJ, Boots, LR, Azziz, R. Prevalence of polycystic ovary syndrome in women seeking treatment for community electrologists. Alabama Professional Electrology Association Society Group. J Reprod Med 1999;44:870–4.Google Scholar
11.Azziz, R, Woods, KS, Reyna, R, et al. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004;89:2745–9.Google Scholar
12.Szulu, M, Morgan, DJ, McLeish, M, et al. Pharmacokinetics of intravenous clomiphene isomers. Br J Clin Pharmacol 1989; 27(5):639–40.Google Scholar
13.Veuse, TD, Chung, AP. Ovulation induction in polycystic ovary syndrome. J Obstet Gynecol Can 2010;32(5),495–502.Google Scholar
14.Elkind-Hirsch, K, Darensbourg, C, Creasy, G, Gipe, D. Conception rates in clomiphene citrate cycles with and without hormone supplementation: a pilot study. Curr Med Res Opin 2005;21(7):1035–40.CrossRefGoogle ScholarPubMed
15.Gysler, M, March, CM, Mishell, DR Jr, Bailey, E. A decade’s experience with an individualized clomiphene treatment regimen including its effect on the post coital test. Fertil Steril 1982;37:161–7.Google Scholar
16.Roy, S, Greenblatt, RB, Mahesh, VB, Jungck, EC. Clomiphene citrate: further observations on its use in induction of ovulation in the human and on its mode of action. Fertil Steril 1963;14:575–95.Google Scholar
17.Dicky, RP, Hotkamp, DE. Development, pharmacology and clinical experience with clomiphene citrate. Hum Reprod Update 1996;2:483–506.CrossRefGoogle Scholar
18.Elnashar, A, Abdelmageed, E, Fayed, M, Sharaf, M. Conception rates in clomiphene citrate cycles with and without hormone supplementation: a pilot study. Curr Med Res Opin 2005;21(7):1035–40.Google Scholar
19.Persanezhad, ME, Alborzi, SA, Jahroni, BN. A prospective double blind randomized placebo controlled clinical trial of bromocriptine in clomiphene resistant patients with polycystic ovarian syndrome and normal prolactin level. Arch Gynecol Obstet 2004;269:125–9.Google Scholar
20.Bayar, U, Basaran, M, Kiran, S, et al. Use of an aromatase inhibitor in patients with polycystic ovarian syndrome: a perspective randomized trial. Fertil Steril 2006;86:1447–51.Google Scholar
21.Mitwally, MFM, Casper, RF. Use of aromatase inhibitor for induction of ovulation in patients with an inadequate response to Clomiphene citrate. Fertil Steril 2001;75:305–9.Google Scholar
22.Al-Omari, W, Al-Hadithi, N, Izat, B, Sulaiman, W. The effect of an aromatase inhibitor on ovulation induction and endometrial receptivity in clomiphene resistant women with polycystic ovary syndrome. Mid East Fertil Soc J 2001;6:52–5.Google Scholar
23.Metawie, MH. Comparative study of aromatase inhibitor, letrozole with clomiphene citrate for induction of ovulation. Mid East Fertil Soc J 2001;6:57–9.Google Scholar
24.Amer, SA, Li, TC, Ledger, WL. Ovulation induction using laparoscopic ovarian drilling in women with polycystic ovarian syndrome: predictors of success. Hum Reprod 2004;19:1719–24.CrossRefGoogle ScholarPubMed
25.Bayram, N, VanWely, M, Kaaijk, EM, et al. Using an electrocautery strategy or recombinant follicle stimulating hormone to induce ovulation in polycystic ovary syndrome: randomized controlled trial. BMJ 2004;328(7433):192.CrossRefGoogle ScholarPubMed
26.Mercorio, F, Mercorio, A, DiSpiezio, Sardo A, et al. Evaluation of ovarian adhesion formation after laparoscopic ovarian drilling by second look mini-laparoscopy. Fertil Steril 2008;89:1229–33.CrossRefGoogle Scholar
27.Kong, GWS, Cheung, LP, Lok, IH. Effects of laparoscopic ovarian drilling in treating infertile anovulatory polycystic ovarian syndrome patients with and without metabolic syndrome. Hong Kong Med J 2011;17:5–10.Google ScholarPubMed
28.Dunaif, A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr Rev 1997;18(6):774–800.Google Scholar
29.Essah, PA, Nestler, JE. Metabolic syndrome in women with polycystic ovary syndrome. Fertil Steril 2006;86:S18–19.CrossRefGoogle ScholarPubMed
30.Scheen, AJ. Clinical pharmacokinetics of metformin. Clin Pharmacokinet 1996;30(5):359–71.Google Scholar
31.Glucophage label and approval history. U.S. Food and Drug Administration. Retrieved January 8, 2007. Data available for download on FDA Website.Google Scholar
32.Lord, JM, Flight, IHK, Norman, RJ. Metformin in polycystic ovary syndrome: systematic review and meta-analysis. BMJ 2003; 327(7421):951–3.CrossRefGoogle ScholarPubMed
33.Legro, RS, Barnhart, HX, Schlaff, WD, et al. Clomiphene, metformin or both for infertility in the polycystic ovary syndrome. N Engl J Med 2007;356:551–66.CrossRefGoogle ScholarPubMed
34.Lunenfeld, B. Treatment of anovulation by human gonadotropins. J Int Fed Gynaecol Obstet 1963;1:153.Google Scholar
35.Rosenberg, E, Coleman, J, Damani, M, Garcia, CR. Clinical effect of postmenopausal gonadotropins. J Clin Endocrinol Metab 1962;23:181–9.Google Scholar
36.Giudice, E, Crisci, C, Eshkol, A, Papoian, R. Composition of commercial gonadotropin preparation extracted from human post menopausal urine: characterization of nongonadotropin proteins. Hum Reprod 1994;9:2291–9.Google Scholar
37.Howles, CM. Genetic engineering of human FSH (Gonal F). Hum Reprod Update 1996;2:172–91.Google Scholar
38.Bayram, N, Van Wely, M, van Der Veen, F. Recombinant FSH versus urinary gonadotropins or recombinant FSH for ovulation induction in subfertility associated with polycystic ovary syndrome. Cochrane Database Syst Rev 2001;(2):CD002121.Google Scholar
39.The Practice Committee of the American Society for Reproductive Medicine. Gonadotropin preparations: past, present, future prospective. Fertil Steril 2008;90:S13–20.CrossRefGoogle Scholar
40.Balash, J. Inducing follicular development in anovulatory patients and normally ovulating women: current concepts and the role of recombinant gonadotropins. In: Gardner, DK, Weissman, A, Howles, CM, Shoham, Z (Eds.) Textbook of Assisted Reproductive Techniques: Laboratory and Clinical Perspective. London, UK: Martin Dunitz, Ltd, 2001:698.Google Scholar
41.Sagle, MA, Kiddy, DS, Franks, S. A comparative randomized study of low dose human menopausal gonadotropin and follicle stimulating hormone in women with polycystic ovarian syndrome. Fertil Steril 1991;55(1):56–60.Google Scholar
42.Nugent, D, Vandekerckhove, P, Hughes, E, et al. Gonadotropin therapy for ovulation induction in subfertility associated with polycystic ovary syndrome. Cochrane Database Syst Rev 2000;(4):CD000410.Google ScholarPubMed
43.DeLeo, V, la Marca, A, Ditto, A, et al. Effects of metformin on gonadotropin induced ovulation in women with polycystic ovary syndrome. Fertil Steril 1999;72:282–5.Google Scholar
44.Jacobs, HS, MacDongall, BA. Polycystic ovaries and ART. In: Gardner, DK, Weissman, A, Howles, CM, Shoham, Z (Eds.) Textbook of Assisted Reproductive Techniques: Laboratory and Clinical Perspective. London, UK: Martin Dunitz, Ltd, 2001:1040.Google Scholar
45.Clark, AM, Thomley, B, Tomlinson, L, et al. Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment. Hum Reprod 1998;13:1502–5.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×