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No
from Section III - Ovarian Cancer
Published online by Cambridge University Press: 20 July 2023
Evidence suggests removal of enlarged supradiaphragmatic nodes (ESDN) at primary debulking does not improve survival. Most patients with ESDN (76%) have multiple nodal sites involved (cardiophrenic, parasternal, mediastinal, axillary, and subclavian) and 45% of them have parenchymal metastases. PET is more sensitive as imaging technique than CT scan. Not all ESDN are metastatic. ESDN are responsive to chemotherapy and isolated ESDN recurrences are rare, 5%. There is no survival difference in Stage IIIC with or without ESDN. Resection of ESDN does not improve survival. Survival with single versus multiple sites of ESDN are similar.
An indication for removal of ESDN might be a rare patient with a single site of ESDN persistent after primary chemotherapy, surgically accessible, and with no residual abdominal disease after completion of an interval debulking, representing a site of unresponsive nodal disease.
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