Critical approaches to research on war-affected societies emphasize the necessity for a more empirically grounded approach to the production of knowledge. Presently, research on war-affected societies is undergoing a shift toward localization with a call for more “voices” with local knowledge and expertise. This research is an attempt to analyze the challenges of reliable knowledge production in war-affected societies and their circulation in academia, the policy-making community, and feeding media discourse. The research focuses on the Russian war against Ukraine since 2014 as a prism through which to examine the main challenges for localized knowledge production. We consider several aspects of knowledge production including the problems and issues of framing and wording that define the character of the conflict, challenges of research design and data collection, researchers’ positioning dilemmas, participants’ responses, differences between policy and academic research, and the role of the media. The purpose of this study is to engage with and attempts to advance the literature on knowledge localization. We argue that a move toward the localization of fieldwork requires a more sensitive and transdisciplinary approach to knowledge production. Based on our own experience of fieldwork during wartime, we point out possible ethical and methodological challenges and offer workable responses to them.