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1 results

  • Case 33 - Drug-Induced Myasthenia Gravis: Immune Checkpoint Inhibitor (ICI)-Related

  • from Disorders of the Neuromuscular Junction
  • Jessica E. Hoogendijk, University Medical Center Utrecht, Marianne de Visser, Amsterdam University Medical Center, Pieter A. van Doorn, Erasmus MC, University Medical Center, Rotterdam, Erik H. Niks, Leiden University Medical Center
  • Book:
    Neuromuscular Disease
    Published online:
    29 November 2024
    Print publication:
    19 December 2024, pp 163-164

  • Summary

    A 73-year-old man was referred by his oncologist because of dyspnoea occurring for one and a half weeks, and high CK levels (1341 U/L). For four years he was treated for a melanoma with pulmonary and cerebral metastases. Treatment included nivolumab that had been started three months previously. The dyspnoea was worse on exertion and when lying down. He also experienced some difficulties speaking clearly, and choking had occurred a few times during the past week. He had no diplopia. The complaints did not fluctuate. There was some recent myalgia, but he had not noticed any muscle weakness.