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This study compared cognitive flexibility (CF) and emotion recognition (ER) in adolescents with eating disorders (ED) to a healthy group.
Methods:
Forty healthy individuals aged 12–18 years with no psychiatric diagnosis and 46 patients diagnosed with anorexia nervosa (AN), bulimia nervosa (BN), or binge eating disorder (BED) according to DSM-5 criteria participated. CF was assessed using the Cognitive Flexibility Scale (CFS), Stroop Test, and Berg Card Sorting Test (BCST), while ER was evaluated using the test of perception of affect via nonverbal cues.
Results:
CFS scores were lower in the ED group compared to the control group. Neuropsychological test results indicated similar BCST perseverative error percentages among ED patients and controls. However, while the BED group demonstrated greater difficulties with inhibitory control, as shown in the Stroop Test, the BN and AN groups performed similarly to the control group. ER performance was similar across groups, although the AN subgroup exhibited heightened recognition of negative emotions, particularly disgust and fear.
Conclusions:
This study highlights unique and shared neurocognitive patterns related to CF and ER profiles of ED patients. Despite self-reports of greater cognitive rigidity among ED patients, objective tests did not consistently confirm it. Notably, BED patients exhibited inhibitory control challenges, aligning with impulsive tendencies. ER abilities were similar to controls; however, the AN subgroup showed heightened sensitivity to certain negative emotions, such as disgust. These findings underscore the need for further research with larger, more balanced samples to explore how CF and ER vary across developmental stages and subtypes.
Variation exists in our attitude and behaviour towards food and exercise, resulting in different degrees of health and ill health. Cultural and economic factors contribute to this, alongside personal choices, leading to a spectrum from normative eating, through disordered eating to the extremes of eating disorders (EDs). Understanding the intricate interplay between biological, psychological, and sociocultural factors to eating, exercise and body image is paramount to understand the current state regarding EDs and to deliver/develop multifaceted and individualised treatments. Significant service developments have occurred following the launch of the Irish Health Service Executive Model of Care for EDs in 2018. However, incomplete roll out and surge in EDs referrals post Covid-19 require generic child and adolescent mental health services (CAMHS) to be competent in assessment of EDs, and to keep abreast of clinical updates in order to offer effective treatment.
This review provides an evidenced based update on eating related difficulties, outlines a useful assessment framework, offers information on appropriate clinical management, and highlights exciting clinically relevant research developments.
Research suggests that those caring for a loved one with an eating disorder in the UK report unmet needs and highlight areas for improvement. More research is needed to understand these experiences on a wider, national scale.
Aims
To disseminate a national survey for adults who had experience caring for a loved one with an eating disorder in the UK, informed by the findings of a smaller scale, qualitative study with parents, siblings and partners in the UK.
Method
A cross-sectional web-based survey was disseminated to adults who had experience caring for a loved one with an eating disorder in the UK.
Results
A total of 360 participants completed the survey. Participants described experiences of care received in both children and young people's, and adult services. Those receiving care from children and young people's services generally reported more timely care, greater involvement in care and more confidence managing their loved one's symptoms post-discharge. In both settings, participants identified a number of areas for improvement, including more timely access to care, improved transition processes and discharge planning, and increased involvement in their loved one's care.
Conclusions
This survey captures the experiences of individuals caring for a loved one with an eating disorder in the UK. There are identified discrepancies between experiences of care in children and young people services compared with adult services. Clinical implications and recommendations for improvement are discussed, including improved transition and discharge processes, increased involvement of and/or support for carers themselves, and more timely access to support services for the unwell individual.
Eating disorders include anorexia nervosa, bulimia nervosa, and binge eating disorder. The treatments with the most research support are cognitive-behavioral therapy, interpersonal psychotherapy, and family based treatment. Credible components of treatment include psychoeducational strategies, nutritional/dietary strategies, exposure therapy, social support, in-session weighing, cognitive strategies, and relapse prevention. A sidebar describes body checking and body avoidance.
Problems in eating behaviors in conjunction with altered cognitions about shape, weight, or food define eating disorders. Behaviors can include restrictive eating patterns, loss-of-control eating episodes, as well as compensatory actions to mitigate caloric intake such as overexercise or vomiting. Cognitive preoccupations can be related to food, eating, body image, and/or weight. Combinations of these behaviors and cognitions define the specific DSM-5 eating disorder diagnoses. Screening by clinicians is important, because many will present for associated comorbidities rather than the eating disorder, and early interventions are associated with better outcomes. Malnutrition, dehydration, infertility, seizures, and cardiac problems are common medical complications of eating disorders. Multiple levels of care can be appropriate for treatment of eating disorders; the least restrictive level that allows the patient to make behavioral changes in eating while still ensuring both medical and psychiatric safety is preferred. Because both physiological and psychological factors are involved in eating pathology, the treatment team should ideally include expertise from medicine, psychiatry, nutrition, and talk therapy. Communication across the team about the patient’s current goals is essential, as all members can influence the patient’s motivation to make changes necessary for recovery.
It is well established that there is a substantial genetic component to eating disorders (EDs). Polygenic risk scores (PRSs) can be used to quantify cumulative genetic risk for a trait at an individual level. Recent studies suggest PRSs for anorexia nervosa (AN) may also predict risk for other disordered eating behaviors, but no study has examined if PRS for AN can predict disordered eating as a global continuous measure. This study aimed to investigate whether PRS for AN predicted overall levels of disordered eating, or specific lifetime disordered eating behaviors, in an Australian adolescent female population.
Methods
PRSs were calculated based on summary statistics from the largest Psychiatric Genomics Consortium AN genome-wide association study to date. Analyses were performed using genome-wide complex trait analysis to test the associations between AN PRS and disordered eating global scores, avoidance of eating, objective bulimic episodes, self-induced vomiting, and driven exercise in a sample of Australian adolescent female twins recruited from the Australian Twin Registry (N = 383).
Results
After applying the false-discovery rate correction, the AN PRS was significantly associated with all disordered eating outcomes.
Conclusions
Findings suggest shared genetic etiology across disordered eating presentations and provide insight into the utility of AN PRS for predicting disordered eating behaviors in the general population. In the future, PRSs for EDs may have clinical utility in early disordered eating risk identification, prevention, and intervention.
DSM-5 differentiates avoidant/restrictive food intake disorder (ARFID) from other eating disorders (EDs) by a lack of overvaluation of body weight/shape driving restrictive eating. However, clinical observations and research demonstrate ARFID and shape/weight motivations sometimes co-occur. To inform classification, we: (1) derived profiles underlying restriction motivation and examined their validity and (2) described diagnostic characterizations of individuals in each profile to explore whether findings support current diagnostic schemes. We expected, consistent with DSM-5, that profiles would comprise individuals endorsing solely ARFID or restraint (i.e. trying to eat less to control shape/weight) motivations.
Methods
We applied latent profile analysis to 202 treatment-seeking individuals (ages 10–79 years [M = 26, s.d. = 14], 76% female) with ARFID or a non-ARFID ED, using the Nine-Item ARFID Screen (Picky, Appetite, and Fear subscales) and the Eating Disorder Examination-Questionnaire Restraint subscale as indicators.
Results
A 5-profile solution emerged: Restraint/ARFID-Mixed (n = 24; 8% [n = 2] with ARFID diagnosis); ARFID-2 (with Picky/Appetite; n = 56; 82% ARFID); ARFID-3 (with Picky/Appetite/Fear; n = 40; 68% ARFID); Restraint (n = 45; 11% ARFID); and Non-Endorsers (n = 37; 2% ARFID). Two profiles comprised individuals endorsing solely ARFID motivations (ARFID-2, ARFID-3) and one comprising solely restraint motivations (Restraint), consistent with DSM-5. However, Restraint/ARFID-Mixed (92% non-ARFID ED diagnoses, comprising 18% of those with non-ARFID ED diagnoses in the full sample) endorsed ARFID and restraint motivations.
Conclusions
The heterogeneous profiles identified suggest ARFID and restraint motivations for dietary restriction may overlap somewhat and that individuals with non-ARFID EDs can also endorse high ARFID symptoms. Future research should clarify diagnostic boundaries between ARFID and non-ARFID EDs.
Machine learning could predict binge behavior and help develop treatments for bulimia nervosa (BN) and alcohol use disorder (AUD). Therefore, this study evaluates person-specific and pooled prediction models for binge eating (BE), alcohol use, and binge drinking (BD) in daily life, and identifies the most important predictors.
Methods
A total of 120 patients (BN: 50; AUD: 51; BN/AUD: 19) participated in an experience sampling study, where over a period of 12 months they reported on their eating and drinking behaviors as well as on several other emotional, behavioral, and contextual factors in daily life. The study had a burst-measurement design, where assessments occurred eight times a day on Thursdays, Fridays, and Saturdays in seven bursts of three weeks. Afterwards, person-specific and pooled models were fit with elastic net regularized regression and evaluated with cross-validation. From these models, the variables with the 10% highest estimates were identified.
Results
The person-specific models had a median AUC of 0.61, 0.80, and 0.85 for BE, alcohol use, and BD respectively, while the pooled models had a median AUC of 0.70, 0.90, and 0.93. The most important predictors across the behaviors were craving and time of day. However, predictors concerning social context and affect differed among BE, alcohol use, and BD.
Conclusions
Pooled models outperformed person-specific models and the models for alcohol use and BD outperformed those for BE. Future studies should explore how the performance of these models can be improved and how they can be used to deliver interventions in daily life.
Edited by
Andrea Fiorillo, University of Campania “L. Vanvitelli”, Naples,Peter Falkai, Ludwig-Maximilians-Universität München,Philip Gorwood, Sainte-Anne Hospital, Paris
Eating disorders (ED) are complex psychiatric disorders associated with high morbidity and mortality. Medical complications are relatively frequent and may involve all organs and systems, and although most remit when a regular food intake and/or a normal body weight are resumed, others are severe enough to cause the death of the individual. Despite this relevance for public health, there is no conclusive knowledge about their etiopathogenesis. Current diagnostic criteria are unable to address all clinical presentations of these syndromes, since they are focused on eating-related psychopathology and miss the presence of general psychopathological symptoms, which have been shown to have a central role in the disorders. Moreover, although social processes and connection with others have been recognized to be a cornerstone of clinical recovery, they are rarely considered in the therapeutic planning. This chapter reviews the recent literature on emerging issues related to the etiopathogenetic risk factors, focusing especially on reward processes. Psychopathology and diagnostic problems are addressed through the illustration of new methodological approaches such as the network analysis and the staging model. Finally, we consider the impact of an ED on interpersonal functioning of close others, parents, partners, and siblings of the individual with an ED.
Timely intervention is beneficial to the effectiveness of eating disorder (ED) treatment, but limited capacity within ED services means that these disorders are often not treated with sufficient speed. This service evaluation extends previous research into guided self-help (GSH) for adults with bulimic spectrum EDs by assessing the feasibility, acceptability, and preliminary effectiveness of virtually delivered GSH using videoconferencing.
Method:
Patients with bulimia nervosa (BN), binge eating disorder (BED) and other specified feeding and eating disorders (OSFED) waiting for treatment in a large specialist adult ED out-patient service were offered virtually delivered GSH. The programme used an evidence-based cognitive behavioural self-help book. Individuals were supported by non-expert coaches, who delivered the eight-session programme via videoconferencing.
Results:
One hundred and thirty patients were allocated to a GSH coach between 1 September 2020 and 30 September 2022; 106 (82%) started treatment and 78 (60%) completed treatment. Amongst completers, there were large reductions in ED behaviours and attitudinal symptoms, measured by the ED-15. The largest effect sizes for change between pre- and post-treatment were seen for binge eating episode frequency (d = –0.89) and concerns around eating (d = –1.72). Patients from minoritised ethnic groups were over-represented in the non-completer group.
Conclusions:
Virtually delivered GSH is feasible, acceptable and effective in reducing ED symptoms amongst those with bulimic spectrum disorders. Implementing virtually delivered GSH reduced waiting times, offering a potential solution for long waiting times for ED treatment. Further research is needed to compare GSH to other brief therapies and investigate barriers for patients from culturally diverse groups.
Labelling specific psychiatric concerns as ‘niche’ topics relegated to specialty journals obstructs high-quality research and clinical care for these issues. Despite their severity, eating disorders are under-represented in high-impact journals, underfunded, and under-addressed in psychiatric training. We provide recommendations to stimulate broad knowledge dissemination for under-acknowledged, yet severe, psychiatric disorders.
From a global perspective, eating disorders are increasingly common, probably because of societal transformation and improved detection. However, research on the impact of migration on the development of eating disorders is scarce, and previously reported results are conflicting.
Aims
To explore if eating disorder symptom prevalence varies according to birth region, parents’ birth region and neighbourhood characteristics, and analyse if the observed patterns match the likelihood of being in specialist treatment.
Method
This study uses data from a large population-based health survey (N = 47 662) among adults in Stockholm, Sweden. A general linear model for complex samples, including adjustment for gender and age, was used to explore self-reported eating disorder symptoms. Odds ratios were calculated for individual symptoms.
Results
Eating disorder symptoms are substantially more common in individuals born abroad, especially for migrants from a non-European country. This holds true for all surveyed symptoms, including restrictive eating (odds ratio 5.5, 95% CI 4.5–6.7), compensatory vomiting (odds ratio 6.1, 95% CI 4.6–8.0), loss-of-control eating (odds ratio 2.6, 95% CI 2.3–3.1) and preoccupation with food (odds ratio 2.3, 95% CI 1.9–2.8). Likewise, symptoms are more common in individuals with both parents born abroad and individuals living in districts with a high percentage of migrant residents. A gap exists between district-level symptom scores and the likelihood of being in specialist eating disorder treatment.
Conclusions
These findings call for oversight of current outreach strategies, and highlight the need for efforts to reduce stigma and increase eating disorder symptom recognition in broader groups.
High mortality rates and poor outcomes from eating disorders, especially anorexia nervosa, are largely preventable and require urgent action. A national strategy to address this should include prevention; early detection; timely access to integrated physical and psychological treatments; safe management of emergencies; suicide prevention; and investment in training, services and research.
This chapter illustrates the complex functions that eating disorder behaviour can take, including self-punishment, emotional avoidance, empowerment, mastery, self-regulation, and appeasement of others. The schema therapy approach encourages disaggregating these functions, personifying them, understanding them, and directing dialogues between them. A case study illustrates the way in which the schema mode model can be applied to work with eating disorder symptoms alongside complex trauma. A sufficient level of medical and nutritional stability (as indicated by blood tests and weight) must be reached in order to provide sufficient safety for therapy to proceed. A key component of schema therapy is to understand the unmet needs and schemas that have led to the development of an eating disorder. In schema therapy, the client gradually learns to reconnect with her/his inner child states and needs through extensive therapeutic work – which includes imagery rescripting, chairwork mode dialogues, and somatic, cognitive, and behavioural techniques. Coping modes are not just bypassed, but through imagery and chairwork are actively acknowledged and integrated to form a Healthy Adult ‘team’ that works to prioritise the inner child modes and ultimately meet the client’s nutritional, physiological, and emotional needs.
Eating disorders are historically underserved in healthcare, but are increasingly prevalent and recognised for their high costs regarding mortality, quality of life and the economy. Those with longstanding eating disorders are commonly labelled ‘severe and enduring’ (SEED), which has been challenged for its conceptual vagueness and potential to discourage patients. Attempts to define individuals from this cohort as having ‘terminal’ illness have also gained traction in recent years. This paper is grounded in lived/living experience and relevant research. It challenges the logical coherence and utility of SEED, arguing that the word ‘enduring’ unhelpfully situates intractability of longstanding illness within patients themselves and the nature of their illness. This risks a sense of inevitability and overlooks the important role of contextual factors such as lacking resources and insufficient evidence for withholding active treatment. Recommendations suggest approaches to dismantling unhelpful binaries between early intervention and intensive support, recovery and decline.
This chapter describes pseudoscience and questionable ideas related to eating disorders (EDs) – anorexia nervosa, bulimia nervosa, and binge eating disorder. The chapter opens by considering challenges associated with assessment and diagnosis. Common myths are explored, such as the idea that all exercise is good exercise. Dubious treatments include group and inpatient treatment, complementary and alternative medicine, online self-help, and fad diets. The chapter closes by reviewing research-supported approaches.
Describes the symptoms and physical consequences of eating disorders. Identifies the symptoms of binge-eating disorder, bulimia nervosa, and anorexia nervosa. Describes the epidemiology of eating disorders. Describes some of the social and cultural factors associated with eating disorders. Compares the various treatments for eating disorders.
Chapter 23 considers the wide range of eating difficulties and disorders that children and young people may experience. We discuss common eating-related difficulties in children including fussy eating and then go on to discuss eating disorders, including anorexia nervosa and bulimia nervosa, and consider how these disorders are diagnosed and treated.
The focus of this chapter is on evolutionary theories and models of anorexia nervosa (AN), bulimia nervosa (BN) and obesity. Although obesity is not considered a mental health problem, its link with binge eating disorder and its massively increased prevalence in recent decades, in association with modernisation and Westernisation together with increased morbidity and mortality, have stimulated much evolutionary theorising. Disorders of eating and weight are of particular interest to evolutionary scholars for a number of reasons. These include the claim that many of these disorders are evolutionarily novel, that they have increased in prevalence in developed countries in recent decades, that they have a large female preponderance, particularly of AN and BN, and that they have an increased risk of mortality. Our poor understanding of the aetiology of eating disorders together with poor outcomes (especially for AN) has been associated with a proliferation of proximate theories/models within mainstream psychiatry but without any one theory gaining wide acceptance. This presents an opportunity for evolutionary models to propose new ways of thinking and new avenues for research on these disorders. A review of the current evolutionary literature on AN and BN shows that despite the wide range and variety of models, the sexual competition hypothesis has, so far, had the strongest empirical support from clinical and non-clinical studies. While other evolutionary theories focus on AN, the sexual competition hypothesis provides an explanation for both AN and BN, as well as for the widespread dieting seen in the population. Furthermore, it uniquely makes sense of the specific presentations of eating disorders in males. Nevertheless, it seems increasingly clear that intrasexual competition is not the whole story. More recent work that considers other areas of mismatch in the modern environment represents a necessary extension to this theoretical perspective. It is concluded that larger-scale studies on clinical populations are required to put these theoretical formulations to the test and to explore their potential clinical utility.
Background: Eating disorders (EDs) are severe psychiatric disorders which, when left untreated, can lead to psychosocial impairment, physical disability and death. In the United Kingdom, many specialist ED services collect routine outcome measures (ROMs) which serve to assess illness severity, patients’ quality of life and function. The repeated collection of ROMs over the course of treatment allows for the objective evaluation of patient progress towards recovery. Recent National Health Service (NHS) guidance on adult ED care in England suggests that all services should use ROMs, not just to track progress, but also to support the achievement of collaboratively identified, person-specific recovery goals, to empower patients and inform individualised treatment. To achieve this objective, clinicians need access to psychometrically sound ROMs which can be utilised in a collaborative and person-centred manner. Traditionally, ROMs have been collected using standardised patient-reported outcome measures (PROMs), but increasingly individualised PROMs (i-PROMs) are also being developed. Methods & Findings: In this talk I will review the ‘why, what and how’ of ROMs, PROMs, I-PROMS and of associated normative and ipsative feedback on these measures in the eating disorders context. Conclusions: Use of PROMs has much to be commended both in regard to treating individual patients, at service level and also the wider health care system.