We present a 15-year retrospective study comparing the epidemiology of Parkinson’s disease (PD) between Chinese and non-Chinese populations in the Greater Toronto Area. A cohort of 88 patients with PD revealed that Chinese patients (N = 36) had a significantly lower mean age at diagnosis (67.3 ± 12.6 years) compared to non-Chinese patients (72.1 ± 9.2 years) (p = 0.039). Higher obesity rates were found in non-Chinese patients (p = 0.0004). Chinese patients experienced more motor fluctuations (p = 0.028) and amantadine use (p = 0.041). These findings underscore the importance of future research on ethnic variations in PD.