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The Effect of Plasma from Schizophrenic Patients on the Chicken Erythrocyte System

Published online by Cambridge University Press:  29 January 2018

A. Mangoni ,
R. Balazs  and
A. J. Coppen
A. Mangoni
Affiliation:
Medical Research Council, Neuropsychiatric Research Unit, Carshalton, Surrey
R. Balazs
Affiliation:
Medical Research Council, Neuropsychiatric Research Unit, Carshalton, Surrey
A. J. Coppen
Affiliation:
Medical Research Council, Neuropsychiatric Research Unit, Carshalton, Surrey
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Frohman et al. (1960a, 1960b, 1961, 1962) have investigated the effect of plasma of schizophrenic patients on carbohydrate metabolism. They measured the production of lactate and pyruvate by the nucleated red cells of the chicken after incubation with patients' plasma. After incubation with plasma from schizophrenic patients, the lactate/pyruvate ratio was raised significantly above the ratio found after incubation with plasma from normal subjects. This observation was interpreted as evidence of an inhibition of aerobic metabolism induced by the plasma of schizophrenic patients. We report here an attempt to confirm these findings.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 109 , Issue 459 , March 1963 , pp. 231 - 234
Copyright
Copyright © Royal College of Psychiatrists, 1963 

References

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