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Psychiatric and Social Outcome of Liver Transplantation

Published online by Cambridge University Press:  02 January 2018

Ian Collis ,
Andrew Burroughs ,
Keith Rolles  and
Geoffrey Lloyd
Ian Collis*
Affiliation:
University College Hospital, London
Andrew Burroughs
Affiliation:
Royal Free Hospital, Hampstead, London NW3 2QG
Keith Rolles
Affiliation:
Royal Free Hospital, Hampstead, London NW3 2QG
Geoffrey Lloyd
Affiliation:
Royal Free Hospital, Hampstead, London NW3 2QG
*
Dr Collis, Department of Psychiatry, University College Hospital, Gower Street, London WC1E 6AU
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Abstract

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Background

This study measures psychiatric morbidity, quality of life, and cognitive function after liver transplantation.

Method

We undertook a cross-sectional study, with a longitudinal subgroup. The setting was a tertiary referral centre for liver transplantation. The subjects were 30 post-liver-transplantation patients, including 11 also interviewed before the operation. The main outcome measures were the Clinical Interview Schedule (CIS), the General Health Questionnaire (GHQ), the Nottingham Health Profile (NHP), and the Mini-Mental State Examination (MMSE).

Results

Of the patients, 8/30 were CIS cases, and 7/30 were GHQ cases. NHP scores were higher than a previous postal study indicated, with less impairment after than before transplant. MMSE scores were 24–30. Median GHQ was 7.0 before operation and 1.0 after operation (P = 0.03), with no significant change in CIS score.

Conclusion

Liver transplantation improves quality of life, but not to the level of the general population; post-transplantation patients have a prevalence of psychiatric morbidity comparable with that of general medical patients.

Type
Papers
Information
The British Journal of Psychiatry , Volume 166 , Issue 4 , April 1995 , pp. 521 - 524
Copyright
Copyright © Royal College of Psychiatrists, 1995 

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