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Familial differences in schizophrenia with good and poor prognosis1

Published online by Cambridge University Press:  09 July 2009

Michael S. McCabe ,
Richard C. Fowler ,
Remi J. Cadoret  and
George Winokur
Michael S. McCabe
Affiliation:
Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, U.S.A.
Richard C. Fowler
Affiliation:
Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, U.S.A.
Remi J. Cadoret
Affiliation:
Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, U.S.A.
George Winokur
Affiliation:
Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, U.S.A.
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Synopsis

Probands with schizophrenia of good and poor prognosis were selected according to defined criteria. Families were investigated blindly. The families with poor prognosis contained significantly more schizophrenia, neurosis, and overall illness, but less affective disorder than the families with good prognosis.

Type
Research Article
Information
Psychological Medicine , Volume 1 , Issue 4 , August 1971 , pp. 326 - 332
Copyright
Copyright © Cambridge University Press 1971

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References

REFERENCES

American Psychiatric Association (1968). Diagnostic and Statistical Manual of Mental Disorders, 2nd edn. DSM II. American Psychiatric Ass: Washington, D.C.Google Scholar
Astrup, C., and Noreik, K. (1966). Functional Psychoses: Diagnostic and Prognostic Models. Thomas: Springfield, Illinois.Google Scholar
Cadoret, R. J., Winokur, G., and Clayton, P. J. (1970). Family history studies: VII. Manic depressive disease versus depressive disease. British Journal of Psychiatry, 116, 625–635.CrossRefGoogle ScholarPubMed
Clayton, P. J., Rodin, L., and Winokur, G. (1968). Family history studios: III. Schizoafiective disorder, clinical and genetic factors including a one to two year follow-up. Comprehensive Psychiatry, 9, 31–49.CrossRefGoogle Scholar
Eitinger, L., Laane, C. L., and Langfeldt, G. (1958). The prognostic value of the clinical picture and the therapeutic value of physical treatment in schizophrenia and the schizophreniform states. Acta psychiatrica et neurologica Scandinavica, 33, 33–53.CrossRefGoogle Scholar
Fish, F. (1964). A guide of the Leonhard classification of chronic schizophrenia. Psychiatric Quarterly, 38, 438–450.CrossRefGoogle ScholarPubMed
Guze, S. B., Goodwin, D. W., and Crane, J. B. (1969). Criminality and Psychiatric disorders. Archives of General Psychiatry, 20, 583–591.CrossRefGoogle ScholarPubMed
Heston, L. L. (1966). Psychiatric disorders in foster home reared children of schizophrenie mothers. British Journal of Psychiatry, 112, 819–825.CrossRefGoogle Scholar
Holmboe, R., and Astrup, C. (1957). A follow-up study of 255 patients with acute schizophrenia and schizophreniform psychoses. Acta psychiatrica et neurologica Scandinavica, 32, Suppl. 115, Munksgaard: Copenhagen.Google Scholar
Kallmann, F. J. (1946). The genetic theory of schizophrenia. Analysis of 691 schizophrenia twin index families. American Journal of Psychiatry, 103, 309–322.CrossRefGoogle ScholarPubMed
Kant, O. (1942). The incidence of psychoses and other mental abnormalities in the families of recovered and deteriorated schizophrenic patients. Psychiatric Quarterly, 16, 176–186.CrossRefGoogle Scholar
Kringlen, E. (1967). Heredity and Environment in the Functional Psychoses. Norwegian Monographs on Medical Science. Universitetsforlaget: Oslo.Google Scholar
Langfeldt, G. (1953). Some points regarding the symptomatology and diagnosis of schizophrenia. Acta psychiatrica Scandinavica, Suppl. 80, 7–26. Munksgaard: Copenhagen.Google Scholar
O'Neal, P., Robins, L. N., King, L. J., and Schaefer, J. (1962). Parental deviance and the genesis of sociopathic personality. American Journal of Psychiatry, 118, 1114–1124.CrossRefGoogle ScholarPubMed
Reich, T., Clayton, P. J., and Winokur, G. (1969). Family history studies: V. The genetics of mania. American Journal of Psychiatry, 125, 1358–1369.CrossRefGoogle ScholarPubMed
Robins, E., and Guze, S. B. (1970). Establishment of diagnostic validity in Psychiatric illness: its application to schizophrenic. American Journal of Psychiatry, 126, 983–987.CrossRefGoogle Scholar
Roth, M. (1959). The phobic anxiety-depersonalization syndrome. Proceedings of the Royal Society of Medicine, 52, 587–595.CrossRefGoogle Scholar
Slater, E., with the assistance of Shields, J. (1953). Psychotic and neurotic illnesses in twins. Medical Research Council Special Report Series No. 278. HMSO: London.Google Scholar
Stenstedt, Å. (1952). A study in Manic-depressive psychosis. Clinical, social and genetic investigations. Acta psychiatrica et neurologica Scandinavica, Suppl. 79, Munksgaard: Copenhagen.Google Scholar
Strömgren, E. (1938). Beitrage zur psychiatrischen Erblehre. Acta Psychiatrica et neurologica Scandinavica, Suppl. 19. Munksgaard: Copenhagen.Google Scholar
Vaillant, G. E. (1962). The prediction of recovery in shizophrenia. Journal of Nervous and Mental Diseuses, 135, 534–543.CrossRefGoogle Scholar
Vaillant, G. E. (1964). Prospective prediction of schizophrenic remission. Archives of General Psychiatry, 11, 509–518.CrossRefGoogle ScholarPubMed
Welner, J., and Strömgren, E. (1958). Clinical and genetic studies on benign schizophreniform psychoses based on a follow-up. Acta psychiatrica Scandinavica, 33, 377–399.CrossRefGoogle ScholarPubMed
Wing, J. K., Birley, J. L. T., Cooper, J. E., Graham, P., and Isaacs, A. D. (1967). Reliability of a procedure for measuring and classifying ‘present Psychiatric state’. British Journal of Psychiatry, 113, 499–515.Google ScholarPubMed