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The use of urinary and recombinant human FSH preparations to induce superovulation in sheep and the effect on FSH and LH concentrations

Published online by Cambridge University Press:  20 November 2017

N.R. Kendall ,
A. Gonzalez-Bulnes  and
B.K. Campbell
N.R. Kendall*
Affiliation:
School of Human Development, University of, Nottingham Q.M.C., Nottingham NG7 2UH, UK Division of Animal Physiology, School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD UK
A. Gonzalez-Bulnes
Affiliation:
Departamento de Reproduccion Animal, SGIT-INIA, Avda. Puerto de Hierro s/n, 28040-Madrid, Spain
B.K. Campbell
Affiliation:
School of Human Development, University of, Nottingham Q.M.C., Nottingham NG7 2UH, UK
*
E-mail: Nigel.Kendall@Nottingham.ac.uk
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Extract

Most ovarian stimulation protocols in ruminants utilise pituitary extracts that contain FSH with varying amounts of LH contamination. Protocols utilising these extracts in sheep generally give superovulation responses that are highly variable in the range of 0-15 ovulations. The use of pure recombinant human FSH (rhFSH) is widespread in clinical medicine. The aims of the study are: a) to determine if rhFSH will induce superovulation in sheep and whether this differs in response to human menopausal gonadotrophin (HMG), which is more similar to pituitary extracts with an equal amount of LH to the FSH; b) to monitor the effect of the human FSH’s on the endogenous LH and FSH concentrations.

Type
Theatre Presentations
Information
Proceedings of the British Society of Animal Science , Volume 2004 , 2004 , pp. 59
Copyright
Copyright © The British Society of Animal Science 2004

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