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Leptin, growth hormone receptor and DGAT1 gene polymorphisms in Holstein cattle
Published online by Cambridge University Press: 23 November 2017
Extract
DNA polymorphisms have been well established for the diacylglycerol acyltransferase 1 (DGAT1), leptin and growth hormone receptor (GHR) genes, and they seem to correlate with several economically important traits in dairy cattle. In particular, a lysine-to-alanine substitution (K232A) and a phenylalanine-to-tyrosine substitution have been described for the DGAT1 (Kaupe et al., 2004) and GHR genes (Aggrey et al., 1999, Blott et al., 2003), respectively. Polymorphisms have also been identified within the leptin gene; for example, one has been found in an intronic sequence (RFLP1) and another inside exon 3 (Liefers et al., 2002). The objective of the present study was to determine the polymorphism status of these three gene loci in Holstein cows raised in Greece.
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- Copyright © The British Society of Animal Science 2008