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Analysis of association between the PrP gene and live weight and slaughter traits in an experimental flock of Swaledale sheep in the UK
Published online by Cambridge University Press: 23 November 2017
Extract
Genetic selection based on polymorphisms identified at codons 136, 154 and 171 of the prion protein (PrP) gene is being implemented in scrapie eradication programs (e.g. Defra, 2005). These programs aim to remove the VRQ allele (associated with the highest incidence of classical scrapie) and increase the frequency of the ARR allele (which confers the highest level of resistance). However, concerns remain about how selection on the PrP gene would affect other economically important traits. The objective of this study was to investigate potential associations between the PrP alleles and lamb traits in an experimental flock of Swaledale sheep, a hill sheep breed.
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- Copyright © The American Society of International Law 2016