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Virus encoded cytokines and cytokine receptors

Published online by Cambridge University Press:  01 December 1997

M. BARRY  and
G. McFADDEN
M. BARRY
Affiliation:
Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2H7
G. McFADDEN
Affiliation:
The John P. Robarts Research Institute, and Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada N6G 2V4
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Abstract

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In order to replicate efficiently within the host, viruses have evolved multiple strategies to evade the host's immune system. In many cases viruses have actually hijacked various components of the host's immune system to ensure their own survival. One such strategy is the expression of virus encoded cytokines and cytokine receptors. Members of the poxvirus and herpesvirus families have been particularly successful with this strategy. The study of virus survival strategies provides important information regarding both virus biology as well as information about the immune system itself.

Keywords

Virokinesviroceptorsherpes virusimmunosubversionpoxvirus
Type
Research Article
Information
Parasitology , Volume 115 , Issue 7 , December 1997 , pp. 89 - 100
Copyright
© 1997 Cambridge University Press