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The utility of complete genome sequences in the study of pathogenic bacteria

Published online by Cambridge University Press:  01 October 1999

D. W. HOOD
Affiliation:
Molecular Infectious Diseases Group, University of Oxford Department of Paediatrics, Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK
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Abstract

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The availability of complete genome sequences is a revolution in the study of microorganisms. A fully annotated genome sequence provides an interactive tool for scientists and influences the approach and focus of research. In this article I discuss the impact of genome sequencing projects of bacteria. Much useful data have been obtained but the experimental methods needed to fully exploit the information continue to develop. Some of the approaches and particular applications relevant to bacteria of clinical importance are discussed.

Type
Research Article
Copyright
© 1999 Cambridge University Press