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Radiotherapy and Perianal Paget's Disease

Published online by Cambridge University Press:  07 March 2006

Kerry Holt  and
Lyndsey Stanley
Kerry Holt
Affiliation:
Radiotherapy, Suffolk Oncology Centre, Ipswich Hospital NHS Trust, UK
Lyndsey Stanley
Affiliation:
Radiotherapy, Suffolk Oncology Centre, Ipswich Hospital NHS Trust, UK
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Abstract

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The aim of this study is to document a case of Extra Mammary Paget's Disease (EMPD), which was treated with radiotherapy at the Suffolk Oncology Centre. We have shown evidence, both in the reviewed literature and in this study, that radiotherapy can be used successfully as a primary form of treatment for this disease.

The patient discussed in this paper had EMPD in the perianal region. 40 Gy in 10# using a parallel-opposed pair field arrangement was prescribed. However due to mental and physical frailty only 90% of the dose could be delivered. The patient suffered only minor side effects and three years post-radiotherapy was still disease free. We can therefore say that radiotherapy was successful in this instance.

We concluded that there is a definite role for radiotherapy in the management of EMPD and that it can be effective as a primary treatment, where the only other option could be mutilating surgery.

Keywords

Extra Mammary Paget's Diseaseperianalmucinradiotherapyanogential regiontreatment
Type
Case Study
Information
Journal of Radiotherapy in Practice , Volume 5 , Issue 1 , March 2006 , pp. 55 - 60
Copyright
2006 Cambridge University Press