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“Ritalin” and Chlorpromazine in Chronic Schizophrenia: a Controlled Clinical Trial

Published online by Cambridge University Press:  08 February 2018

Barbara J. Salisbury  and
E. H. Hare
Barbara J. Salisbury
Affiliation:
Consultant Psychiatrist Warlingham Park Hospital, Surrey
E. H. Hare
Affiliation:
Consultant Psychiatrist Warlingham Park Hospital, Surrey
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Ritalin (methylphenidate) is a drug which was developed by the firm of Ciba Limited. It resembles amphetamine in its central stimulant and sympathomimetic action but has quite a different chemical structure. Its general properties have been described by Meier et al. (1954) and by Drassdo and Schmidt (1954 a, b). Geller (1955) and Stier (1955) used Ritalin in the treatment of depressive states associated with apathy, while Ferguson (1955) found it of value in countering the depressive effects of reserpine therapy. Ferguson also notes that Ritalin seemed to have a beneficial action in cases of chronic schizophrenia and considered that his findings warranted a clinical trial.

Type
Original Articles
Information
Journal of Mental Science , Volume 103 , Issue 433 , October 1957 , pp. 830 - 834
Copyright
Copyright © Royal College of Psychiatrists, 1957 

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