Hostname: page-component-745bb68f8f-d8cs5 Total loading time: 0 Render date: 2025-02-06T03:10:22.092Z Has data issue: false hasContentIssue false
  • English
  • Français

Observations on the Short-Acting Relaxant Ro/3/0386

Published online by Cambridge University Press:  08 February 2018

R. B. Taylor
R. B. Taylor*
Affiliation:
Whittingham Hospital, Preston
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The present investigation covers a series of 110 treatments with electroplexy in which RO/3/0386 has been used as an ultra short-acting relaxant. This is a heteropoly-methylene-bis-trimethylammonium diiodide, Me3N + (CH2)4. S. S. (CH2)4N + Me3. 2I in aqueous solution which, being related to the decamethonium compounds, acts by depolarizing the motor end plate, and results in similar clinical effects to those produced by succinylcholine as described recently by Richards and Youngman (1952), Mayrhofer (1952), Bourne Collier and Somers (1952), and others.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 99 , Issue 414 , January 1953 , pp. 156 - 157
Copyright
Copyright © Royal College of Psychiatrists, 1953 

References

Bourne, J. G., Collier, H. O. J., and Somers, G. F., Lancet, 1952, i, 1225.Google Scholar
Hurley, M. J., and Monro, A. B., Brit. Med. J., 1952, i, 1027.Google Scholar
Hewer, C. L., ibid., 1952, i, 971.Google Scholar
Mayrhofer, O. K., ibid., 1952, i, 1332.Google Scholar
Richards, H., and Youngman, H. R., ibid., 1952. i, 1334.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.