Hostname: page-component-745bb68f8f-mzp66 Total loading time: 0 Render date: 2025-02-11T09:14:39.913Z Has data issue: false hasContentIssue false

Investigations into Glutamic Acid Metabolism in Schizophrenics

Published online by Cambridge University Press:  08 February 2018

Poul Astrup
Affiliation:
From the Psychiatric Department (Senior Physician: Villars Lunn) and the Medical Department B (Senior Physician: Erik Warburg) of Rigshospitalet, University of Copenhagen, Denmark, and from the Central Laboratory of the Blegdam Hospital (Director: Poul Astrup), Copenhagen, Denmark
Henning G⊘tzsche
Affiliation:
From the Psychiatric Department (Senior Physician: Villars Lunn) and the Medical Department B (Senior Physician: Erik Warburg) of Rigshospitalet, University of Copenhagen, Denmark, and from the Central Laboratory of the Blegdam Hospital (Director: Poul Astrup), Copenhagen, Denmark
Bj⊘rn Ibsen And
Affiliation:
From the Psychiatric Department (Senior Physician: Villars Lunn) and the Medical Department B (Senior Physician: Erik Warburg) of Rigshospitalet, University of Copenhagen, Denmark, and from the Central Laboratory of the Blegdam Hospital (Director: Poul Astrup), Copenhagen, Denmark
Ib Munkvad
Affiliation:
From the Psychiatric Department (Senior Physician: Villars Lunn) and the Medical Department B (Senior Physician: Erik Warburg) of Rigshospitalet, University of Copenhagen, Denmark, and from the Central Laboratory of the Blegdam Hospital (Director: Poul Astrup), Copenhagen, Denmark
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Earlier investigations (3, 4) have shown an abnormal glutamic acid metabolism in schizophrenic patients.

These changes are, briefly, low glutamic acid level (and high glutamine level) especially in acute cases. Glutamic acid concentrations below 1.2 milli grams per 100 ml. venous blood were ascertained in most of these patients.

Type
Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1955 

References

1. Astrup, P., and Munkvad, I., “On the determination of glutamine and glutamic acid in plasma”, Scand. Jour. Clin. and Lab. Invest., 1950, 2, 133.Google Scholar
2. Krebs, H. A., “Quantitative determination of glutamine and glutamic acid”, Biochem. J., 1948, 43, 51.CrossRefGoogle Scholar
3. Munkvad, I., “Glutaminsyre og glutaminbestemmelser i plasma paa et psykiatrisk patientmateriale”, Thesis, 1951, Copenhagen.Google Scholar
4. Idem , “Determinations of glutamine and glutamic acid in a material of mental patients”, Preliminary report. Acta psych. et neurol., 1950, 25, 269.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.