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The Galactose Tolerance Test in Phenylketonuria

Published online by Cambridge University Press:  08 February 2018

Valerie A. Cowie
Valerie A. Cowie*
Affiliation:
From The Fountain Hospital, Tooting Grove, S.W.17
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In cases where there is known to be a disturbance of metabolism it is natural to speculate upon the possible site of dysfunction in the organs and tissues of the body.

In phenylketonuria the basic biochemical error is a disordered metabolism of phenylalanine, the patient being unable to dispose of this substance at a normal rate (Jervis et al., 1940). The phenylpyruvic acid in the urine of phenylketonuric patients is derived from a deamination of phenylalanine in the kidney.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 96 , Issue 404 , July 1950 , pp. 799 - 800
Copyright
Copyright © Royal College of Psychiatrists, 1950 

References

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Penrose, L. S. (1939), “Peripheral nerve tumours in a case of phenylketonuria,” Lancet, i, 572.CrossRefGoogle Scholar
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