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Further Studies on the Modified Takata Reaction (M.T.R.) on the Cerebrospinal Fluids of Neurological and Psychiatric Patients

Published online by Cambridge University Press:  08 February 2018

H. H. Fleischhacker
H. H. Fleischhacker*
Affiliation:
From the Pathological Laboratory, Shenley Hospital (Middlesex County Council), Shenley, Herts
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Ucko (1935) showed that the reaction time of the Takata test on serum can be reduced from 24 hours to 90 minutes by modifying the concentration and volume of the reagents. These reagents were applied with a further slight modification in the amount of the fluid tested and as a one-tube method for cerebrospinal fluid (Fleischhacker, 1938). 177 cerebrospinal fluids were examined, and the conclusion was drawn that the M.T.R. will indicate even very fine disturbances in the protein composition of cerebrospinal fluid. Later the test, together with others, was applied to another 165 C.S.Fs. from neurological and psychiatric patients and was found to give weak positive results in many psychoses of the so-called “non-organic” type (especially typical schizophrenics), while it remained negative in manic depressives and neurotic disorders (Fleischhacker, 1943).

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 91 , Issue 384 , July 1945 , pp. 353 - 371
Copyright
Copyright © Royal College of Psychiatrists, 1945 

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