In this paper the author has put together some general observations suggested by his exceptional experience in the treatment of the inebriate. It is noteworthy that, on the whole, his attitude is distinctly optimistic. In the first place he pleads for more discrimination of cases. He distinguishes three classes of inebriates: (1) paroxysmal cases, where there are often premonitory symptoms in change of character, morbid impulses, etc., treatment of which may abort the attack; (2) delusional inebriates with mental exaltation, which may be prodromal to general paralysis; for such cases rest and change with eliminative and subsequently tonic treatment are indicated; and (3) senile and demented cases.