Hostname: page-component-745bb68f8f-hvd4g Total loading time: 0 Render date: 2025-02-11T08:43:30.976Z Has data issue: false hasContentIssue false
  • English
  • Français

Clinical Studies of a New Barbiturate (Nealbarbitone)

Published online by Cambridge University Press:  08 February 2018

A. A. Robin ,
D. P. Cronin  and
L. Scotton
A. A. Robin
Affiliation:
From Runwell Hospital and Southend General Hospital, Essex
D. P. Cronin
Affiliation:
From Runwell Hospital and Southend General Hospital, Essex
L. Scotton
Affiliation:
From Runwell Hospital and Southend General Hospital, Essex
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Brandström (1957) in Sweden, has recently resolved certain problems in the synthesis of barbiturates with a neopentyl group as one of the ring substituents and the resulting compound 5-allyl-5-neopentyl-barbituric acid∗ has been subjected to experimental studies which show it to be less hypnotic and anaesthetic than amylobarbitone or pentobarbitone sodium and yet protective to rats subjected to a stress situation after the technique of Jacobsen and Sonné (1955). The drug is rapidly absorbed after oral administration, and has a duration of action between that of amylobarbitone and phenobarbitone.

Type
Original Articles
Information
Journal of Mental Science , Volume 107 , Issue 446 , January 1961 , pp. 83 - 89
Copyright
Copyright © Royal College of Psychiatrists, 1961 

References

Brandström, A., Proc. XVIe Cong. pure appl. chem., 1957, 2, 298.Google Scholar
Bross, I., Biometrics, 1952, 8, 188.CrossRefGoogle Scholar
Curran, F. J., J. Nerv. Ment. Dis., 1944, 100, 142.CrossRefGoogle Scholar
Dalton, K., Brit. Med. J., 1959, 1, 148.CrossRefGoogle Scholar
Davies, D. C., and Shepherd, M., Lancet, 1955, 2, 117.CrossRefGoogle Scholar
Gershon, S., and Shaw, F. H., Brit. Med. J., 1957, 2, 1509.CrossRefGoogle Scholar
Jacobsen, E., and Sonné, E., Acta Pharmacol. et Toxicol., 1955, 11, 135.CrossRefGoogle Scholar
Raymond, M. J., et al., Brit. Med. J., 1957, 2, 63.CrossRefGoogle Scholar
Registrar General, Statistical Review of England and Wales for the Year 1953, Part 1, Medical, 1954. London: H.M.S.O. Google Scholar
Robin, A. A., J. Ment. Sci., 1959, 105, 1064.CrossRefGoogle Scholar
Ryde, C., Svanska Läkartidningen, 1959, 56, 260.Google Scholar
Scott, P. A. L., J. Ment. Sci., 1955, 101, 163.CrossRefGoogle Scholar
Seigel, S., Non Parametric Statistics, 1956, New York: McGraw-Hill.Google Scholar
Trautner, E. M., et al., Brit. Med. J., 1957, 2, 1514.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.