This part maintains the excellence of the preceding parts of this important work. It deals with exophthalmic goitre, acromegaly, general exfoliative epidemic dermatitis, and unilateral hypertrophy of the face, and thus pipes some of the lesser tunes in the grand orchestral performance of Disease. Exophthalmic goitre is carefully considered and admirably illustrated. Under the ætiology reference is made to Gautier's classification of cases into primary and secondary, or into idiopathic and symptomatic, the latter being held to result from some obvious peripheral lesion, and upon this division Bramwell comments as to the impossibility of drawing sharply such a line; he thinks, however, that a practical therapeutic value may attach to the classification. This is no doubt a just view, for the idiopathic diseases, so-called, are everywhere suffering encroachment, proximate causes revealing themselves to the careful inquirer.