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Parotid duct carcinoma arising in bilateral chronic sialadenitis

Published online by Cambridge University Press:  29 June 2007

R. P. Hogg*
Affiliation:
Department of Otolaryngology/Head and Neck Surgery, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK
C. Ayshford
Affiliation:
Department of Otolaryngology/Head and Neck Surgery, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK
J. C. Watkinson
Affiliation:
Department of Otolaryngology/Head and Neck Surgery, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK
*
Address for correspondence: Mr R. P. Hogg, B.Sc., F.R.C.S., Department of Otolaryngology, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH. Fax: 0121 627 2299 e-mail: rchard.hogg@virgin.net
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Abstract

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It is well recognized that, in general, chronic inflammation can predispose to malignant change. There is however, to our knowledge, no previously reported association between chronic obstructive sialadenitis and salivary gland epithelial malignancy. We describe here the first reported example in the English literature of a salivary duct carcinoma arising in a parotid gland with a long history of chronic obstructive sialadenitis. It is possible that a causal relationship exists between the two conditions. If this were the case then non-surgically treated chronic obstructive sialadenitis patients may well warrent careful clinical follow-up.

Type
Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1999

References

Felix, A., El-Naggar, A. K., Press, M. F., Ordonez, N. G., Fonseca, I., Tucker, S. L., Luna, M. A., Batsakis, J. G. (1996) Prognostic significance of biomarkers (c-erbB-2, p53, proliferating cell nuclear antigen, and DNA content) in salivary duct carcinoma. Human Pathology 27: 561566.Google Scholar
Kumar, R. V., Kini, L., Bhargava, A. K., Mukherjee, G., Hazarika, D., Shenoy, A. M., Anantha, N. (1993) Salivary duct carcinoma. Journal of Surgical Oncology 54: 193198.CrossRefGoogle ScholarPubMed
Lewis, J. E., McKinney, B. C., Weiland, L. H., Ferreiro, J. A., Olsen, K. D. (1996) Salivary duct carcinoma. Clinicopathologic and immunohistochemical review of 26 cases. Cancer 77: 223230.Google Scholar
Schroder, M., Droese, M. (1977) Bilateral salivary duct carcinoma of the parotid gland (author's translation). Laryngologie Rhinlogie Otologie (Stuttgart) 56: 907911.Google Scholar