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Management of upper airway obstruction secondary to warfarin therapy: the conservative approach

Published online by Cambridge University Press:  08 March 2006

Mingyann Lim
Affiliation:
Department of Otolaryngology, Great Western Hospital, Swindon, UK
Meena Chaudhari
Affiliation:
Department of Otolaryngology, Great Western Hospital, Swindon, UK
Pablo M Devesa
Affiliation:
Department of Otolaryngology, Great Western Hospital, Swindon, UK
Angus Waddell
Affiliation:
Department of Otolaryngology, Great Western Hospital, Swindon, UK
Deepak Gupta
Affiliation:
Department of Otolaryngology, Great Western Hospital, Swindon, UK
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Abstract

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Airway obstruction secondary to bleeding from warfarin therapy is difficult to manage and uncommon but has been previously described. Previous reports have emphasized the need for reversal of therapy using vitamin K and fresh frozen plasma (FFP). Where a definitive airway has been required, cricothyroidotomy or tracheostomy seem to have been favoured. Several authors have reported failed attempts at endotracheal intubation due to the obstructive effects of a sublingual haematoma. We report here a case which illustrates how endotracheal intubation can be used successfully under the right conditions. It also highlights the superiority of prothrombin complex concentrate over FFP in achieving rapid reversal of abnormal international normalized ratio in the emergency situation.

Type
Online Only Clinical Record
Copyright
© 2005 JLO (1984) Limited