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Hyalinizing clear cell carcinoma of the base of the tongue

Published online by Cambridge University Press:  08 March 2006

R. Balakrishnan ,
Dipak Ranjan Nayak ,
Suresh Pillai  and
Lakshmi Rao
R. Balakrishnan
Affiliation:
Department of ENT and Head and Neck Surgery, Kasturba Medical College, Manipal, India.
Dipak Ranjan Nayak
Affiliation:
Department of ENT and Head and Neck Surgery, Kasturba Medical College, Manipal, India.
Suresh Pillai
Affiliation:
Department of ENT and Head and Neck Surgery, Kasturba Medical College, Manipal, India.
Lakshmi Rao
Affiliation:
Department of Pathology, Kasturba Medical College, Manipal, India.
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Abstract

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Clear cell carcinoma of the salivary glands is a rare tumour that represents less than one per cent of all salivary tumours. They are divided into a biphasic, epithelial-myoepithelial carcinoma and a monophasic pattern which may be myoepithelial or ductal in origin. The latter is accompanied by prominent fibrohyaline stroma and has been described recently as hyalinizing clear cell carcinoma (HCCC).

Most of the HCCC occur in the oral cavity, and are associated with minor salivary glands, unlike the biphasic pattern which is more common in the major salivary glands. In the oral cavity, the commonest site is the palate followed by the lips and the buccal mucosa. Its occurrence in the oropharynx and the larynx is extremely rare.

Keywords

TongueCarcinoma
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 116 , Issue 10 , October 2002 , pp. 851 - 853
Copyright
© Royal Society of Medicine Press Limited 2002