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Effect of Ringer-Lactate and isotonic saline solutions on mucociliary clearance of tracheal epithelium: an experimental study in rats

Published online by Cambridge University Press:  08 March 2006

Murat Ünal  and
Hakki Oktay Seymen
Murat Ünal
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, School of Medicine, Mersin University, Mersin, Turkey.
Hakki Oktay Seymen
Affiliation:
Department of Physiology, Cerrahpasa School of Medicine, Istanbul University, Istanbul, Turkey.
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Abstract

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Isotonic saline solution is frequently used in nasal and tracheal lavage. In a previous clinical study, it was found that Ringer-Lactate solution, as a nasal lavage, was better for mucociliary clearance function than isotonic saline solution after nasal septal surgery. In this experimental study, the effects of Ringer-Lactate and isotonic saline solutions on mucociliary clearance of healthy rat tracheal epithelium were investigated by measuring the transport of carbon particles. We found that tracheal segments that were irrigated with Ringer-Lactate had better mucociliary transport than those irrigated with isotonic saline (p = 0.035).

Keywords

Nasal Lavage FluidMucociliary ClearanceCarbon
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 116 , Issue 7 , July 2002 , pp. 536 - 538
Copyright
© Royal Society of Medicine Press Limited 2002