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Detection of occult nasopharyngeal primary tumours by means of in situ hybridization

Published online by Cambridge University Press:  29 June 2007

R. Feinmesser ,
M. Feinmesser ,
J. L. Freeman ,
A. M. Noyek  and
N. Livni
R. Feinmesser*
Affiliation:
Department of Otolaryngology, Mount Sinai Hospital, University of Toronto, Toronto, Canada.
M. Feinmesser
Affiliation:
Deparment of Pathology, Hadassah Medical Centre, The Hebrew University, Jerusalem, Israel.
J. L. Freeman
Affiliation:
Department of Otolaryngology, Mount Sinai Hospital, University of Toronto, Toronto, Canada.
A. M. Noyek
Affiliation:
Department of Otolaryngology, Mount Sinai Hospital, University of Toronto, Toronto, Canada.
N. Livni
Affiliation:
Deparment of Pathology, Hadassah Medical Centre, The Hebrew University, Jerusalem, Israel.
*
Dr R. Feinmesser, Head, Department of ENT, Beilinson Medical Centre, Sackler School of Medicine, Tel-Aviv University, 49100 Petah-Tiqva, Israel.
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Abstract

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Detection of nasopharyngeal carcinoma primaries in patients presenting with neck node metastases may sometimes demand considerable efforts. By using the ‘ in situ hybridization’ technique, wemanage to identify the Epstein-Barr virus in neck metastases secondary to nasopharyngeal carcinomas. We propose that such identification in neck node metastases where the primary lesion is unknown indicates a nasopharyngeal primary.

Keywords

Nasopharyngeal neoplasmsNeoplasms, unknown primaryHybridization
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 4 , April 1992 , pp. 345 - 348
Copyright
Copyright © JLO (1984) Limited 1992

References

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