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Acute laryngeal paralysis induced by the migration of a totally implantable venous access device’s catheter tip

Published online by Cambridge University Press:  08 March 2006

S. Hervé ,
C. Conessa ,
J. Desrame ,
O. Chollet ,
S. Talfer  and
J. L. Poncet
S. Hervé
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, Hôpital du Val de Grâce, 75005 Paris, France
C. Conessa
Affiliation:
Department of Medicine, Hôpital du Val de Grâce, 75005 Paris, France
J. Desrame
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, Hôpital du Val de Grâce, 75005 Paris, France
O. Chollet
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, Hôpital du Val de Grâce, 75005 Paris, France
S. Talfer
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, Hôpital du Val de Grâce, 75005 Paris, France
J. L. Poncet
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, Hôpital du Val de Grâce, 75005 Paris, France
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Abstract

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The authors report a case of acute vagus nerve paralysis that appeared during a course of chemotherapy. The drugs had been administered through a totally implantable venous access device (TIVAD), whose catheter tip had migrated into the right internal jugular vein (IJV) and was surrounded by a complete venous thrombosis. The supposed aetiology of this paralysis was a leakage of the cytotoxic drug (5-fluorouracil) from the vessel wall into the surrounding carotid space, because of the stagnation of the chemotherapeutic agent above the thrombosis. Four months after cessation of chemotherapy, the laryngeal paralysis was still evident.

Keywords

Central Venous CatheterizationFluorouracilRecurrent Laryngeal NerveVocal Cord Paralysis
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 118 , Issue 3 , March 2004 , pp. 237 - 239
Copyright
© Royal Society of Medicine Press Limited 2004