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Pneumomediastinum following Ecstasy (methylenedioxymetamphetamine, MDMA) ingestion in two people at the same ’rave’

Published online by Cambridge University Press:  08 March 2006

Darius Rejali
Affiliation:
Department of Cardiothoracic Surgery, Manchester Royal Infirmary, UK.
Paul Glen
Affiliation:
Department of Cardiothoracic Surgery, Manchester Royal Infirmary, UK.
Nicholas Odom
Affiliation:
Department of Cardiothoracic Surgery, Manchester Royal Infirmary, UK.
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Abstract

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Ecstasy is a class A controlled drug often consumed by the young population for recreational purposes. Documented complications of its use include hyperpyrexia, disseminated intravascular coagulation (DIC), renal failure and rhabdomyolysis. We report on two patients who developed pneumomediastinum after Ecstasy abuse. Both patients obtained and consumed the drug at the same establishment and presented to the same hospital within half an hour. The possible pathogenesis of this complication are discussed and the literature reviewed. Pneumomediastinum should be recognized as a possible complication of Ecstasy use. Conservative management is appropriate.

Type
Research Article
Copyright
© Royal Society of Medicine Press Limited 2002