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Transmission electron microscopical studies of the site of attachment of Ancylostoma ceylanicum To the small bowel mucosa of the dog

Published online by Cambridge University Press:  05 June 2009

S. M. Carroll ,
T. A. Robertson ,
J. M. Papadimitriou  and
D. I. Grove
S. M. Carroll
Affiliation:
Departments of Medicine and Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia 6009
T. A. Robertson
Affiliation:
Departments of Medicine and Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia 6009
J. M. Papadimitriou
Affiliation:
Departments of Medicine and Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia 6009
D. I. Grove
Affiliation:
Departments of Medicine and Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia 6009
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Abstract

The host-parasite interaction at the site of attachment of the adult hookworm, Ancylostoma ceylanicum, to the small bowel mucosa of the dog has been examined by transmission electron microscopy. The lamina propria around the heads of the worms showed intense infiltration with neutrophilic and cosinophilic leucocytes, and plasma cells were also prominent. Erythrocytcs were cxtravasatcd within the lamina propria while the portions of mucosa engulfed into the buccal cavities of the worms were nccrotic and included aggregates of collagen fibres. Within the lumina of the worms were erythrocytcs in varying stages of lysis together with other nccrotic debris.The mucous membrane adjacent to the heads of the worms was ulcerated while more distant cntcrocytcs were small, distorted and displayed various degrees of microvillar loss. Many mucosal blood vessels had platelet aggregates within their iumina but no fibrin deposition was observed. Vessels were often seen in the bases of the ulcers and were prone to rupture. Erythrocytcs and leucocytes were seen in the dog intestinal lumen in close proximity to the bodies of the worms.

Type
Research Article
Information
Journal of Helminthology , Volume 58 , Issue 4 , December 1984 , pp. 313 - 320
Copyright
Copyright © Cambridge University Press 1984

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References

REFERENCES

Carroll, S. M., Grove, D. I., Dawkins, H. J. S., Mitchell, G. F. & Whitten, L. K. (1983) Infections with a Malaysian dog strain of Ancylostoma ceylanicum in outbred, inbred and immunocompromiscd mice. Parasitology, 87, 229–238.CrossRefGoogle ScholarPubMed
Eiff, J. A. (1966) Nature of an anticoagulant from the cephalic glands of Ancylostoma caninum. Journal of Parasitology, 52, 833–843.CrossRefGoogle ScholarPubMed
Graham, R. & Karnovsky, M. J. (1966) The early stages of absorption of injected horseradish peroxidase in proximal tubules of mouse kidney. Ultrastructural cytochemistry by a new technique. Journal of Histochemistry and Cytochemistry, 14, 291–302.Google Scholar
Kalkofen, U. P. (1970) Attachment and feeding behaviour of Ancylostoma caninum. Zeitschrift fur Parasitenkunde, 33, 339–354.CrossRefGoogle ScholarPubMed
Kalkofen, U. P. (1974) Intestinal trauma resulting from feeding activities of Ancylostoma caninum. American Journal of Tropical Medicine and Hygiene, 23, 1046–1053.CrossRefGoogle ScholarPubMed
Lendrum, A. C., Fraser, D. S., Slidders, W. & Henderson, R. (1962) Studies on the character and staining of fibrin. Journal of Clinical Pathology, 15, 401–413.CrossRefGoogle ScholarPubMed
Miller, T. A. (1979) Hookworm infection in man. In: Advances in Parasitology (editors, Lumsden, W. H. R., Muller, R. & Baker, J. R.), 17, 315–384, Academic Press, London.Google Scholar
Riddle, J. M. & Barnhart, M. I. (1965) The eosinophil as a source for profibrinolysin in acute inflammation. Blood, 25, 777–793.Google Scholar
Roche, M. & Layrisse, M. (1966) The nature and causes of ‘hookworm anemia’. American Journal of Tropical Medicine and Hygiene, 15, 1031–1102.CrossRefGoogle ScholarPubMed
Schwartz, B. (1920) Hemolysins from parasitic worms: preliminary paper. Archives of Internal Medicine, 26, 431–435.CrossRefGoogle Scholar
Spellman, G. G. & Nossel, H. L. (1971) Anticoagulant activity of the dog hookworm. American Journal of Physiology, 220, 922–927.CrossRefGoogle ScholarPubMed
Thompson, R. C. A., Dunsmore, J. D. & Hayton, A. R. (1979) Echinococcus granulosus. Secretory activity of the rostellum of the adult cestbde in situ in the dog. Experimental Parasitology, 48, 144–163.CrossRefGoogle ScholarPubMed