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Inhibitory activity of bovine milk osteopontin and its fragments on the formation of calcium phosphate precipitates

Published online by Cambridge University Press:  19 July 2006

Haruto Kumura ,
Natsuko Minato  and
Kei-ichi Shimazaki
Haruto Kumura
Affiliation:
Laboratory of Dairy Food Science, Division of Bioresources and Product Science, Research faculty of Agriculture, Hokkaido University, Sapporo-shi 060-8589, Japan
Natsuko Minato
Affiliation:
Laboratory of Dairy Food Science, Division of Bioresources and Product Science, Research faculty of Agriculture, Hokkaido University, Sapporo-shi 060-8589, Japan
Kei-ichi Shimazaki
Affiliation:
Laboratory of Dairy Food Science, Division of Bioresources and Product Science, Research faculty of Agriculture, Hokkaido University, Sapporo-shi 060-8589, Japan
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Abstract

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Osteopontin (OPN) is an acidic phosphorylated glycoprotein found in many tissues and physiological fluids. OPN is known to possess multiple biological functions including bone remodeling, cell adhesion, cellular transformation and immunological mediation; these functions have been extensively reviewed (Butler et al. 1996; Sodek et al. 2000).

Keywords

osteopontincasein phosphopeptidecalcium phosphate
Type
Research Article
Information
Journal of Dairy Research , Volume 73 , Issue 4 , November 2006 , pp. 449 - 453
Copyright
Proprietors of Journal of Dairy Research 2006