Five fire-cured tobacco varieties were grown under different fertilizer levels and environments, to investigate their effects upon quality of the cured leaf. Environment exerted the greatest effect, and the best quality of leaf was produced from virgin soils. Fertilizer responses were greatest in environments where traditional agricultural methods operated, but even heavy applications of fertilizer under these conditions did not compensate for lack of good initial soil conditions. Although variety affected the style of tobacco produced, varietal differences were small compared with the effects of environment and fertilizer.