Wheat is one of the most important crops worldwide. It covers the largest area under any single crop in the world and is the third most-produced cereal after maize and rice. It is a staple food for billions of people. Diseases cause significant yield and quality losses in wheat and are thus a major threat to global food security. The book Disease Resistance in Wheat is an excellent attempt to address the substantial problems associated with various diseases in wheat and provides an important overview regarding the economic importance, disease symptoms, epidemiology and breeding history along with various means to mitigate and control the challenges imposed by these diseases. The book has been divided into 15 chapters, each describing a building block of the latest technology/information to deal with major wheat diseases caused by fungi, viruses, nematodes and bacteria. There are several tables (sources of resistance and genes), diagrams and images that enable the reader to get an in-depth understanding of the guiding principles behind molecular and conventional breeding strategies of disease management. In general, this is an excellent overview of the current literature, molecular and conventional breeding tools to breed wheat cultivars with better and improved resistance. The book is presented in a logical format making it suitable for a wide range of readers, including plant breeders, pathologists, agronomists, policy makers, farmers and graduate and undergraduate students engaged in the field of plant protection. In my opinion, it is a worthwhile addition to one's bookshelf.