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Allocation concealment and blinding in clinical trials

Published online by Cambridge University Press:  18 May 2011

Andrea Cipriani ,
Michela Nosè  and
Corrado Barbui
Andrea Cipriani*
Affiliation:
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Michela Nosè
Affiliation:
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Corrado Barbui
Affiliation:
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
*
Address for correspondence: Dr. A. Cipriani, Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, (Italy). Fax: +39-045-585.871 E-mail: andrea.cipriani@univr.it
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Abstract

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Keywords

blindingallocation concealmentrandomisationrandomised controlled trialsstatistics
Type
ABC of Methodology
Information
Epidemiology and Psychiatric Sciences , Volume 17 , Issue 2 , June 2008 , pp. 115 - 116
Copyright
Copyright © Cambridge University Press 2008

References

REFERENCES

Altman, D.G. & Bland, J.M. (1999). Statistics notes. Treatment allocation in controlled trials: why randomise? British Medical Journal 318. 1209.CrossRefGoogle ScholarPubMed
Altman, D.G. & Schulz, K.F. (2001). Statistics notes: concealing treatment allocation in randomised trials. British Medical Journal 323. 446–447.CrossRefGoogle ScholarPubMed
Barbui, C, Veronese, A. & Cipriani, A. (2007). Explanatory and pragmatic trials. Epidemiologia e Psichiatria Sociale, 16, 124–125.CrossRefGoogle ScholarPubMed
Devereaux, P.J., Manns, B.J. & Ghali, W.A. (2001). Physician interpretations and textbook definitions of blinding terminology in randomized controlled trials. Journal of American Medical Association 285, 2000–2003.CrossRefGoogle ScholarPubMed
Schulz, K.F. & Grimes, D.A. (2002). Allocation concealment in randomised trials: defending against deciphering. Lancet 359, 614–618.CrossRefGoogle ScholarPubMed