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Genetic diversity among toxigenic and nontoxigenic Vibrio cholerae O1 isolated from the Western Hemisphere

Published online by Cambridge University Press:  15 May 2009

F. Chen ,
G. M. Evins ,
W. L. Cook ,
R. Almeida ,
N. Hargrett-Bean  and
K. Wachsmuth
F. Chen
Affiliation:
Laboratory for Microbial and Biochemical Sciences, Georgia State University, Atlanta, Georgia 30303
G. M. Evins
Affiliation:
Enteric Bacteriology Section, Division of Bacterial Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333
W. L. Cook
Affiliation:
Laboratory for Microbial and Biochemical Sciences, Georgia State University, Atlanta, Georgia 30303
R. Almeida
Affiliation:
Enteric Bacteriology Section, Division of Bacterial Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333
N. Hargrett-Bean
Affiliation:
Statistical Services Activity, Division of Bacterial Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333
K. Wachsmuth
Affiliation:
Enteric Bacteriology Section, Division of Bacterial Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333
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Summary

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Multilocus enzyme electrophoresis was used to examine genetic relationships among and between toxigenic and non-toxigenic isolates of Vibrio cholerae O1 obtained from patients and the environment in the US Gulf Coast and surrounding areas. A total of 23 toxigenic and 23 non-toxigenic strains were examined. All the toxigenic and 7 of the non-toxigenic strains had the same alleles at 16 enzyme loci, whereas the balance of the nontoxigenic strains had 9 distinct combinations of alleles. This study suggests that all of the toxigenic strains belong to a single clone, and that while some of the non-toxigenic isolates were related, most were of diverse origin.

Type
Research Article
Information
Epidemiology & Infection , Volume 107 , Issue 1 , August 1991 , pp. 225 - 233
Copyright
Copyright © Cambridge University Press 1991

References

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