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Pharmacologic Mood Destabilization: Case Vignettes

Published online by Cambridge University Press:  07 November 2014

Alan C. Swann
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Extract

Bipolar disorder is an illness characterized by inherent mood instability that produces a predisposition to depressive, hypomanic, or manic episodes. This predisposition to affective episodes, rather than the episodes themselves (which can have many causes), is arguably the hallmark of bipolar disorder.

Most episodes of bipolar disorder, including the first episode, are depressive. This exposes an inherent flaw in our nosological system, which requires a manic or hypomanic episode for diagnosis of bipolar disorder. Treatment of a depressive episode in undiagnosed bipolar disorder can entail the use of medications that were developed to treat a different disorder (major depressive illness) and that may have mood-destabilizing or activating properties.

Type
Expert Panel Supplement
Information
CNS Spectrums , Volume 14 , Issue S11: Clinical Decisions for Acute and Mixed Manic Episodes of Bipolar Disorder: A Case-based Approach , November 2009 , pp. 9 - 11
Copyright
Copyright © Cambridge University Press 2009

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