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Aerobic capacity in adults with tetralogy of Fallot

Published online by Cambridge University Press:  15 August 2006

Per Morten Fredriksen ,
Judith Therrien ,
Gruschen Veldtman ,
Mohammed Ali Warsi ,
Peter Liu ,
Erik Thaulow  and
Gary Webb
Per Morten Fredriksen
Affiliation:
University of Toronto Congenital Cardiac Centre for Adults, Toronto General Hospital, Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada
Judith Therrien
Affiliation:
University of Toronto Congenital Cardiac Centre for Adults, Toronto General Hospital, Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada
Gruschen Veldtman
Affiliation:
University of Toronto Congenital Cardiac Centre for Adults, Toronto General Hospital, Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada
Mohammed Ali Warsi
Affiliation:
University of Toronto Congenital Cardiac Centre for Adults, Toronto General Hospital, Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada
Peter Liu
Affiliation:
University of Toronto Congenital Cardiac Centre for Adults, Toronto General Hospital, Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada
Erik Thaulow
Affiliation:
Rikshospitalet (The National Hospital), University of Oslo, Children's Clinic, Pediatric Heart Section, Oslo, Norway
Gary Webb
Affiliation:
University of Toronto Congenital Cardiac Centre for Adults, Toronto General Hospital, Heart and Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada
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Abstract

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Background: We investigated the aerobic capacity of 168 adult patients who had undergone successful surgical repair of tetralogy of Fallot at the University of Toronto Congenital Cardiac Centre for Adults. Methods: We compared values of peak uptake of oxygen, peak heart rate, forced vital capacity, and forced expiratory volume in 1 second to predicted values for their age groups. Results: The patients who had undergone surgical repair of tetralogy of Fallot demonstrated an overall diminished peak uptake of oxygen, at 51%, and peak heart rate, at 79%, compared to predicted values. No difference in peak aerobic capacity was found according to the initial surgical strategy of palliation or repair. Conclusions: Adult patients who have undergone surgical repair of tetralogy of Fallot have lower peak uptake of oxygen, and peak heart rate, compared to predicted values. The reduction in the peak heart rate may affect their exercise capacity. The peak uptake of oxygen also decreased with increasing age at the time of testing, and the age at surgical repair.

Keywords

Congenital heart diseasecardiopulmonary testspirometry
Type
Original Article
Information
Cardiology in the Young , Volume 12 , Issue 6 , December 2002 , pp. 554 - 559
Copyright
2002 Cambridge University Press