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Stress, LTP, and depressive disorder

Published online by Cambridge University Press:  01 December 1997

I. C. Reid  and
C. A. Stewart
I. C. Reid
Affiliation:
Department of Psychiatry, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotlandc.a.stewart@dundee.ac.uk www.dundee.ac.uk/psychiatry
C. A. Stewart
Affiliation:
Department of Psychiatry, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotlandc.a.stewart@dundee.ac.uk www.dundee.ac.uk/psychiatry
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Abstract

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Preoccupation with LTP as a putative memory mechanism may have retarded the consideration of pathological modulation of synaptic plasticity in clinical disorders where memory dysfunction is not a primary feature. Encouraged by Shors & Matzel's review, we consider the relationship between stress, synaptic plasticity, and depressive disorder.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 20 , Issue 4 , December 1997 , pp. 626 - 627
Copyright
© 1997 Cambridge University Press