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Paradoxical sleep and schizophrenia have the same neurobiological support

Published online by Cambridge University Press:  15 June 2005

Claude Gottesmann
Claude Gottesmann*
Affiliation:
Laboratoire de Neurobiologie Comportementale, Faculté des Sciences, Université de Nice-Sophia Antipolis, 06108 Nice Cedex 2, France
*
gottesma@unice.fr
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Abstract:

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During the paradoxical dreaming sleep stage, characterized by hallucinations and delusions, as in schizophrenia, the increased subcortical release of dopamine, the presynaptic inhibition of thalamic relay nuclei, and serotonergic disinhibition are in accordance with the model for the mechanism of hallucination-induction.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 27 , Issue 6 , December 2004 , pp. 794 - 795
Copyright
Copyright © Cambridge University Press 2004