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LTP and learning: Let's stay together

Published online by Cambridge University Press:  01 December 1997

Robert D. Hawkins
Robert D. Hawkins
Affiliation:
Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University and New York State Psychiatric Institute, New York, NY 10032 rhawkins@nypimail.cpmc.columbia.edu
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Abstract

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The hypothesis that there is a 1:1 correspondence between LTP and learning is simplistic, and the correlation approach to testing it is therefore too limited. The alternative hypothesis that LTP plays a role in arousal is consistent with activity-dependent neuromodulation, but ignores the Hebbian properties of LTP. LTP may involve both types of mechanisms, suggesting a possible synthesis of the two hypotheses.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 20 , Issue 4 , December 1997 , pp. 620 - 621
Copyright
© 1997 Cambridge University Press