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A causal relationship between LTP and learning? Has the question been answered by genetic approaches?

Published online by Cambridge University Press:  01 December 1997

Robert Gerlai
Robert Gerlai
Affiliation:
Neuroscience Department, Genentech, Inc. South San Francisco, CA 94080-4990 gerlai@gene.com
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Abstract

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Gene targeting has generated a great deal of data on the molecular mechanisms of long-term potentiation and its potential role in learning and memory. However, the interpretation of some results has been questioned. Compensatory mechanisms and the contribution of genetic background may make it difficult to unequivocally prove the existence of a causal (genetic) link between LTP and learning.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 20 , Issue 4 , December 1997 , pp. 617 - 618
Copyright
© 1997 Cambridge University Press