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But the schizophrenia connection . . .

Published online by Cambridge University Press:  01 June 1999

Jeffrey A. Gray
Affiliation:
Department of Psychology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdomj.gray@iop.bpmf.ac.uk
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Abstract

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As well as data indicating relationships (emphasised in the target article) (1) between dopaminergic transmission in the nucleus accumbens and positive incentive motivation, and (2) between dopaminergic transmission and extraversion, other data (not accounted for by the hypotheses developed in the target article) indicate relationships (3) between accumbens dopaminergic transmission and cognitive, especially perceptual, processes that are disrupted in schizophrenia, and (4) between dopaminergic transmission and psychoticism. The tension between relationships 1 + 2 and 3 + 4 is discussed and a tentative resolution proposed.

Type
Open Peer Commentary
Copyright
© 1999 Cambridge University Press