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Taste Sensitivity to Phenylthiourea Among Leprosy and Filarial Patients in Coastal Andhra Pradesh

Published online by Cambridge University Press:  27 January 2025

B.R. Busi
B.R. Busi*
Affiliation:
Department of Anthropology, Andhra University, Waltair, AP, India
*
Department of Anthropology, Andhra University, Waltair, AP, India

Summary

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Taste blindness for PTC has been studied in (a) 416 leprosy patients and 424 healthy subjects, and (b) 261 filarial patients and 136 normal individuals of both sexes. A significant difference was found between leprosy patients and the healthy control group in the proportion of nontasters (χ 2 = 4.096, for 1 DF, P〈0.05). No significant difference could be observed between the filariasis and the control group (χ 2 = 0.605, for 1 DF, P〉0.30).

Riassunto

Riassunto

La sensibilità gustativa alla PTC è stata studiata in (a) 416 pazienti di lebbra e 424 controlli e (b) in 261 pazienti di filariasi e 136 controlli di ambedue i sessi. Mentre una differenza significativa per la proporzione di non-gustatori è stata riscontrata fra lebbrosi e controlli (χ 2 = 4.096, P〈0.05 per 1 gl), nessuna differenza significativa è stata riscontrata fra pazienti di filariasi e controlli (χ 2 = 0.605, P〉0.30 per 1 gl).

Résumé

Résumé

Le goût pour la PTC a été étudié chez (a) 416 patients de lèpre et 424 contrôles et (b) chez 261 patients de filariose et 136 contrôles des deux sexes. Tandis qu'une différence significative dans la proportion de nongoûteurs a été trouvée entre patients de lèpre et contrôles (χ 2 = 4.096, P〈0.05 pour 1 dl), aucune différence significative n'a été trouvée entre patients de filariose et contrôles (χ 2 = 0.605, P〉0.30 pour 1 dl).

Zusammenfassung

Zusammenfassung

Untersuchung des Geschmacks für PTC bei (a) 416 Leprakranken und 424 Kontrollen und (b) 261 Filariasefällen und 136 Kontrollen beiderlei Geschlechts. Der Anteil der Nichtschmecker war bei Leprakranken und Kontrollen sehr unterschiedlich (χ 2 = 4.096, P〈0.05 für 1 Fg); zwischen den Filariasekranken und ihren Kontrollen hingegen bestand kein wesentlicher Unterschied (χ 2 = 0.605, P〉0.30 für 1 Fg).

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 21 , Issue 4 , October 1972 , pp. 332 - 336
Copyright
Copyright © The International Society for Twin Studies 1972

References

REFERENCES

Akesson, H.O. 1958. Taste sensitivity to phenylthiourea in tuberculous and diabetes mellitus. Ann. Hum. Genet., Lond., 23: 262–265.CrossRefGoogle Scholar
Beiguelman, B. 1962. Reacão gustativa a feniltiocarbamida (PTC) e lepra. Rev. Bras. Leprol., 30: 111–124.Google Scholar
Beiguelman, B. 1964a. Taste sensitivity to phenylthiourea among patients affected with both tuberculosis and leprosy. Acta Genet. Med. Gemellol., 13: 190–192.CrossRefGoogle ScholarPubMed
Beiguelman, B. 1964 b. Taste sensitivity to phenylthiourea and leprosy. Acta Genet. Med. Gemellol., 13: 193–196.CrossRefGoogle ScholarPubMed
Beiguelman, B., Marques, M.B. 1964. Taste sensitivity to phenylthiourea and drugs with antileprotic effect. Acta Genet. Med. Gemellol., 13: 200–202.CrossRefGoogle ScholarPubMed
Brand, N. 1963. Taste sensitivity and endemic goitre in Israel. Ann. Hum. Genet., Lond., 26: 321–324.CrossRefGoogle ScholarPubMed
Brand, N. 1964. Taste response and poliomyelitis. Ann. Hum. Genet., Lond., 27: 233–239.CrossRefGoogle ScholarPubMed
Chung, C.S., Witkop, C.J., Henry, J.L. 1964. A genetic study of dental caries with special reference to PTC taste sensitivity. Am. J. Hum. Genet., 16: 231.Google ScholarPubMed
Fraser, G.R. 1961. Cretinism and taste sensitivity to phenylthiocarbamide. Lancet, 1: 964–965.CrossRefGoogle ScholarPubMed
Harris, H., Kalmus, H. 1949. The measurement of taste sensitivity to phenylthiourea (PTC). Ann. Eugen., Lond., 15: 24–31.CrossRefGoogle Scholar
Harris, H., Kalmus, H., Trotter, W.R. 1949. Taste sensitivity to phenylthiourea in goitre and diabetes. Lancet, 11: 1038.CrossRefGoogle Scholar
Kalmus, H. 1957. Defective colour vision, PTC tasting and drepanocytosis in samples from fifteen Brazilian populations. Ann. hum. Genet., 21: 313.CrossRefGoogle ScholarPubMed
Kitchin, F.D., Howel-Evans, W., Clarke, C.A., Mc Connel, R.B., Sheppard, P.M. 1959. PTC taste response and thyroid disease. Br. Med. J., 1: 1069–1074.CrossRefGoogle ScholarPubMed
Saldanha, P.H. 1956. Apparent pleiotropic effect of genes determining taste thresholds for phenylthiourea. Lancet 11: 74.CrossRefGoogle Scholar
Sheppard, T.H. II, Gartler, S.M. 1960. Increased incidence of non-tasters of phenylthiocarbamide among congenital athyreotic cretins. Science, 131: 929.CrossRefGoogle Scholar
Terry, M.C., Segall, G. 1947. The association of diabetics and taste blindness. J. Hered., 38: 135–137.CrossRefGoogle ScholarPubMed
Terry, M.C. 1950. Taste blindness and diabetics in the colored population of Jamaica. J. Hered., 41: 306–307.CrossRefGoogle Scholar